Results 81 to 90 of about 76,033 (333)

LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver

open access: yesAdvanced Materials, EarlyView.
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim   +12 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

Association Between White-Coat Effect and Blunted Dipping of Nocturnal Blood Pressure [PDF]

open access: yes, 2017
Background In this study, we assessed whether the white-coat effect (difference between office and daytime blood pressure (BP)) is associated with nondipping (absence of BP decrease at night).
Bochud, Murielle   +7 more
core  

Precision Diagnostics in Sports‐Related Traumatic Brain Injury: Pathophysiology, Biomarker Development and Emerging Technologies

open access: yesAdvanced Sensor Research, EarlyView.
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol   +3 more
wiley   +1 more source

Pseudo and resistant hypertension: A chaotic perspective

open access: yesThe Journal of Clinical Hypertension, 2022
Systemic blood pressure (BP) may oscillate for homeostatic needs (equilibrium by constancy) or just as shifts in other intrinsic and extrinsic variables known as allostatic changes. This transitory pressure often rises alerts physicians to out‐of‐control
Heitor Moreno
doaj   +1 more source

Cost analysis of ambulatory blood pressure monitoring in initiating antihypertensive drug treatment in Australian general practice [PDF]

open access: yes, 2002
The document attached has been archived with permission from the editor of the Medical Journal of Australia. An external link to the publisher’s copy is included.Objective: To compare the cost of ambulatory blood pressure monitoring (ABPM) with the ...
Ewald, Ben   +1 more
core  

Resistant/Refractory Hypertension and Sleep Apnoea: Current Knowledge and Future Challenges [PDF]

open access: yes, 2019
Hypertension is one of the most frequent cardiovascular risk factors. The population of hypertensive patients includes some phenotypes whose blood pressure levels are particularly difficult to control, thus putting them at greater cardiovascular risk ...
Barbé Illa, Ferran   +7 more
core   +2 more sources

Tie2‐Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke

open access: yesAdvanced Science, EarlyView.
This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss   +9 more
wiley   +1 more source

Column: Hypertension Nursing - White coat hypertension

open access: yesOnline Brazilian Journal of Nursing, 2006
White coat hypertension is defined by hypertensive blood pressure in the office, whereas blood pressure in other situations is normal, for example in ambulatory blood pressure monitoring or home blood pressure measurement.
Angela Maria Geraldo Pierin
doaj  

Unattended automated office blood pressure measurement in children

open access: yesBlood Pressure, 2021
Purpose We studied the performance of unattended automated office blood pressure (uAOBP) measurement in children, in relation to oscillometric office BP (OBP) and ambulatory blood pressure monitoring (ABPM).
Tomáš Seeman   +4 more
doaj   +1 more source

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