Results 51 to 60 of about 2,207,366 (294)

Agency, Responsibility, and Culpability: The Complexity of Roles and Self-representations of Perpetrators

Journal of Perpetrator Research, 2018
How much agency perpetrators have during genocide is highly contested and significant for dealing with the past after the end of conflict. In this context, ascriptions of roles such as perpetrators, bystanders and victims are drawn upon to delineate ...
Timothy Williams
doaj   +1 more source

Modalități de reprezentare a femininului la Mariana Bojan / Way of representing the feminine at Mariana Bojan [PDF]

Incursiuni în imaginar, 2016
Affiliated at the Equinox magazine poetic group, Mariana Bojan debuted in 1976 with Elegy for the last grove, a book that allowed us to identify, with enough precision, some of the poet's obvious qualities and first of all the taste for a diminutive ...
Ioana Maria Pașca
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Comic innocence

The European Journal of Humour Research
In recent years, humour has re-entered the public sphere as a serious and potentially explosive topic of debate, giving rise to social conflicts and controversies.
Dick Zijp
doaj   +1 more source

Expert facial comparison evidence: Science versus pseudo science

Психология и право, 2016
Confirming the identity of the accused is a critical component of many criminal trials. However, recent evidence suggests this process is highly error prone and leads to unacceptably high rates of wrongful conviction (Innocence Project, 2015).
McNeill Allan, Suchomska Monika, Strathie Ailsa   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Presuming Innocence

, 2012
I discuss two questions about the meaning and implications of the Presumption of Innocence. First, is it consistent with laying either an evidential or a persuasive burden on the defendant at trial?
Duff, R A, RA Duff
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source