Results 81 to 90 of about 160,024 (306)

Turning the Corner on Mass Incarceration? [PDF]

open access: yes, 2011
For the first time in forty years, the national incarceration rate is flattening out, even falling in state prisons. For the first time in three decades, the number of adults under any kind of correctional supervision—in prison or jail or on probation or
Cole, David
core   +1 more source

Postcard from the ICTY [PDF]

open access: yes, 2018
This chapter examines a postcard which is readily available at the International Criminal Tribunal for the Former Yugoslavia. As an object of international criminal law, the postcard reveals a great deal about the aims of international criminal law, and ...
Rigney, Sophie
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Reclaiming Adolescent Sexuality: Images of Girlhood in Petra Collins’s Babe

open access: yesAdeptus, 2017
Reclaiming Adolescent Sexuality: Images of Girlhood in Petra Collins’s Babe This paper examines photographs, drawings, collages and other art forms collected in the book Babe, edited by photographer Petra Collins and published by Prestel in 2015.
Aleksandra Kamińska
doaj   +1 more source

The Substance of False Confessions [PDF]

open access: yes, 2010
A puzzle is raised by cases of false confessions: How could an innocent on convincingly confess to a crime? Postconviction DNA testing has now exonerated over 250 convicts, more than forty of whom falsely confessed to rapes and murders.
Garrett, Brandon L.
core   +1 more source

The Execution of the Innocent [PDF]

open access: yes, 1998
Radelet and Bedau discuss the continuing and regular incidence of American trial courts sentencing innocent defendants to death, which was one of the problems that gave rise to the ABA\u27s moratorium on capital ...
Bedau, Hugo Adam, Radelet, Michael L.
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

'We were not part of apartheid': rationalisations used by four white pre-service teachers to make sense of race and their own racial identities

open access: yesSouth African Journal of Education, 2014
Despite fundamental reforms to South African education, large performance gaps still prevail between former black schools and former white schools. Nineteen years into a democracy and education in post-apartheid South Africa still retains a strong racial
Adré le Roux
doaj  

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