Results 141 to 150 of about 3,224,961 (325)

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

White Matter Integrity and Episodic Memory Performance in Mild Cognitive Impairment: A Diffusion Tensor Imaging Study

, 2009
Felicia C. Goldstein, Hui Mao, Liya Wang, Chunchun Ni, James J. Lah, Allan I. Levey   +5 more
openalex   +1 more source

Generation of Functional Dopamine Neurons from Neural Precursor Cells Isolated from the Subventricular Zone and White Matter of the Adult Rat Brain Using Nurr1 Overexpression [PDF]

, 2007
Jaewon Shim, Chang‐Hwan Park, Yong-Chul Bae, Jin-Young Bae, Seungsoo Chung, Mi‐Yoon Chang, Koh H, Hyun‐Seob Lee, Se Jin Hwang, Ki-Hwan Lee, Yong‐Sung Lee, Cha‐Yong Choi, Sang‐Hun Lee   +12 more
openalex   +1 more source

Apolipoprotein E promotes white matter remodeling via the Dab1‐dependent pathway after traumatic brain injury [PDF]

, 2020
Zhijian Huang, Fang Cao, Yue Wu, Jianhua Peng, Jianjun Zhong, Yong Jiang, Cheng Yin, Zongduo Guo, Xiaochuan Sun, Li Jiang, Chongjie Cheng   +10 more
openalex   +1 more source

2D Multi-Class Model for Gray and White Matter Segmentation of the Cervical Spinal Cord at 7T [PDF]

, 2021
Nilser J. Laines Medina, Charley Gros, Julien Cohen‐Adad, Virginie Callot, Arnaud Le Troter   +4 more
openalex   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Chronic Ethanol (EtOH) Consumption Differentially Alters Gray and White Matter EtOH Methyl ¹H Magnetic Resonance Intensity in the Primate Brain

, 2013
Christopher D. Kroenke, Graham S. Flory, Byung Park, Jessica K. Shaw, Andrew R. Rau, Kathleen A. Grant   +5 more
openalex   +1 more source

Effect of Patient Sex on White Matter Alterations in Unilateral Medial Temporal Lobe Epilepsy with Hippocampal Sclerosis Assessed by Diffusion Tensor Imaging [PDF]

, 2012
Kader Karlı Oğuz, İrsel Tezer, Eser Sanverdi, Arzu Ceylan Has, Burçak Bilginer, Anıl Dolgun, Serap Saygı   +6 more
openalex   +1 more source