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Vanishing white matter disease
The Lancet Neurology, 2006Vanishing white matter disease (VWM) is one of the most prevalent inherited childhood leucoencephalopathies. The classical phenotype is characterised by early childhood onset of chronic neurological deterioration, dominated by cerebellar ataxia. VWM is unusual because of its clinically evident sensitivity to febrile infections, minor head trauma, and ...
van der Knaap, Marjo S. +2 more
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Neurogenetics: white matter matters
Trends in Neurosciences, 2002A group of inherited syndromes characterized by progressive muscle atrophy and sensory dysfunction, collectively referred to as Charcot–Marie–Tooth disease (CMT), has proven to be a hotbed for the identification of novel genetic mutations. CMT syndromes are unusually common (affecting one in every 2200 people), can be dominant, recessive or X-linked ...
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Annual Review of Neuroscience, 2016
Progress in magnetic resonance imaging (MRI) now makes it possible to identify the major white matter tracts in the living human brain. These tracts are important because they carry many of the signals communicated between different brain regions. MRI methods coupled with biophysical modeling can measure the tissue properties and structural features ...
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Progress in magnetic resonance imaging (MRI) now makes it possible to identify the major white matter tracts in the living human brain. These tracts are important because they carry many of the signals communicated between different brain regions. MRI methods coupled with biophysical modeling can measure the tissue properties and structural features ...
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White matter hyperintensities — location matters
Nature Reviews Neurology, 2023openaire +2 more sources
Journal of the American Academy of Child & Adolescent Psychiatry, 1995
I K, Lyoo +3 more
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I K, Lyoo +3 more
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White Matter Injury Mechanisms
Current Molecular Medicine, 2004White matter of the brain and spinal cord is susceptible to anoxia, ischemia, trauma and autoimmune attack. Irreversible injury to this tissue can have serious consequences for the overall function of the CNS through disruption of signal transmission. Like neurons, central myelinated axons are critically dependent on a continuous supply of oxygen and ...
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White matter integrity, fiber count, and other fallacies: The do's and don'ts of diffusion MRI
NeuroImage, 2013Derek K. Jones, T. Knösche, R. Turner
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