Results 91 to 100 of about 298,577 (257)

Effects of lipopolysaccharide-induced inflammation on expression of growth-associated genes by corticospinal neurons [PDF]

, 2006
Background: Inflammation around cell bodies of primary sensory neurons and retinal ganglion cells enhances expression of neuronal growth-associated genes and stimulates axonal regeneration.
Anderson, PN, Hossain-Ibrahim, MK, Lieberman, AR, MacNally, JK, Mason, MRJ, Rezajooi, K   +5 more
core   +2 more sources

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Gray matter atrophy in multiple sclerosis despite clinical and lesion stability during natalizumab treatment.

PLoS ONE, 2018
BackgroundBrain volume loss is an important surrogate marker for assessing disability in MS; however, contribution of gray and white matter to the whole brain volume loss needs further examination in the context of specific MS treatment.ObjectivesTo ...
Fredrika Koskimäki, Jacqueline Bernard, Jeong Yong, Nancy Arndt, Timothy Carroll, Seon-Kyu Lee, Anthony T Reder, Adil Javed   +7 more
doaj   +1 more source

Behavioural clusters and predictors of performance during recovery from stroke [PDF]

, 2017
We examined the patterns and variability of recovery post-stroke in multiple behavioral domains. A large cohort of first time stroke patients with heterogeneous lesions was studied prospectively and longitudinally at 1-2 weeks, 3 months and one year post-
Corbetta, Maurizio, Lang, C. E, Ramsey, L. E, Shulman, G. L, Siegel, J. S, Strube, M   +5 more
core   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Depressive symptoms related to low fractional anisotropy of white matter underlying the right ventral anterior cingulate in older adults with atherosclerotic vascular disease

Frontiers in Human Neuroscience, 2015
We sought to characterize the relationship between integrity of the white matter underlying the ventral anterior cingulate (vAC) and depressive symptoms in older adults with atherosclerotic vascular disease (AVD), a condition associated with preferential
Kelly Rowe Bijanki, Kelly Rowe Bijanki, Joy Tamiko Matsui, Joy Tamiko Matsui, Helen S Mayberg, Vincent eMagnotta, Stephan eArndt, Stephan eArndt, Hans J Johnson, Hans J Johnson, Peggy eNopoulos, Sergio eParadiso, Sergio eParadiso, Laurie eMcCormick, Jess eFiedorowicz, Jess eFiedorowicz, Eric eEpping, David eMoser   +17 more
doaj   +1 more source

Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions.

Brain : a journal of neurology, 2020
Multiple sclerosis is a chronic inflammatory, demyelinating disease, although it has been suggested that in the progressive late phase, inflammatory lesion activity declines.
N. Fransen, Cheng-Chih Hsiao, M. van der Poel, Hendrik J. Engelenburg, Kim Verdaasdonk, Maria C. J. Vincenten, E. Remmerswaal, T. Kuhlmann, M. Mason, J. Hamann, J. Smolders, I. Huitinga   +11 more
semanticscholar   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Volumetric analysis of the damage and response of non-invasive brain stimulation in patients with spatial neglect after stroke: a subgroup analysis of the ELETRON trial [PDF]

Brazilian Journal of Medical and Biological Research
This study aimed to analyze the compromised cortical and subcortical brain structures and quantify the volume of ischemic lesions in patients with hemispatial neglect after stroke treated with transcranial direct current stimulation (tDCS).
M.A. Januzzi, G.J. Luvizutto, L.A. Miranda, T.R. da Silva, F.C. Winckler, S.G.Z. Bazan, T.G.S. Edwards, O.M. Pontes-Neto, R. Bazan, L.E. Betting   +9 more
doaj   +1 more source