Results 111 to 120 of about 298,577 (257)

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

White matter tract density index is associated with disability in multiple sclerosis

Neurobiology of Disease
Background: The association between common neuroradiological markers of multiple sclerosis (MS) and clinical disability is weak. Given that the disability in patients with MS may depend on the underlying structural connectivity of the brain, our study ...
Minhoe Kim, Ji Won Seo, Myung Sub Kim, Kyung Hoon Lee, Minchul Kim   +4 more
doaj   +1 more source

The perception of touch and the ventral somatosensory pathway [PDF]

, 2017
Preusser et al. use MRI-based lesion-symptom mapping to confirm the causal role of a ventral pathway in the perception of touch. This pathway originates downstream of the postcentral gyrus in the parietal operculum, passes the insula and the putamen ...
Blankenburg, Felix, Draganski, Bogdan, Driver, Jon, Kosatschek, Anna, Pleger, Burkhard, Preusser, Sven, Roggenhofer, Elisabeth, Rook, Carolin, Thiel, Sabrina D., Villringer, Arno   +9 more
core  

Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions.

Journal of the American Medical Association (JAMA), 2019
Importance The effect of intensive blood pressure lowering on brain health remains uncertain. Objective To evaluate the association of intensive blood pressure treatment with cerebral white matter lesion and brain volumes.
I. Nasrallah, N. Pajewski, A. Auchus, G. Chelune, A. Cheung, Maryjo L. Cleveland, L. Coker, M. Crowe, W. Cushman, J. Cutler, C. Davatzikos, L. Desiderio, J. Doshi, G. Erus, Lawrence J. Fine, S. Gaussoin, Darrin Harris, K. Johnson, P. Kimmel, M. Tamura, L. Launer, A. Lerner, C. Lewis, J. Martindale-Adams, C. Moy, L. Nichols, S. Oparil, P. Ogrocki, Mahboob Rahman, S. Rapp, D. Reboussin, M. Rocco, B. Sachs, K. Sink, K. Sink, C. Still, M. Supiano, Joni K. Snyder, V. Wadley, J. Walker, D. Weiner, P. Whelton, Valerie Wilson, N. Woolard, J. Wright, C. Wright, J. Williamson, R. Bryan   +47 more
semanticscholar   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome. [PDF]

, 2018
The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis.
Bacova, Maria, Bimbova, Katarina, Fedorova, Jana, Galik, Jan, Jachova, Jana, Kisucka, Alexandra, Lukacova, Nadezda, Marsala, Martin, Papcunova, Stefania, Pavel, Jaroslav, Stropkovska, Andrea, Zavacky, Peter   +11 more
core   +2 more sources

An Out‐of‐Place Etiology: Recognizing FMR1 Premutation in the Memory Clinic

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The FMR1 gene premutation (55–200 CGG repeats) is usually associated with a wide range of symptoms and phenotypes within the Fragile X‐tremor/ataxia syndrome (FXTAS), but may also manifest as predominant or isolated cognitive decline. We describe three male patients referred for progressive cognitive impairment and behavioral changes. Standard
Guido Greco, Caterina Motta, Enrica Marchionni, Maria Rosaria D'Apice, Carlangelo Carrese, Giuseppe Novelli, Alessandro Martorana, Chiara Giuseppina Bonomi   +7 more
wiley   +1 more source

Downbeat nystagmus elicited by eyelid closure [PDF]

, 2014
We describe a patient with downbeat nystagmus (DBN) evoked only by eye closure. Brain and spinal cord magnetic resonance imaging revealed a T2 paramedian lesion in the left lower basis pontis and other white matter lesions consistent with multiple ...
Amorim, M, Cunha, L, Lemos, J, Paiva, A, Pereira, D, Santiago, B   +5 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Quantitative histomorphometry of capillary microstructure in deep white matter

NeuroImage: Clinical, 2019
White matter lesions represent a major risk factor for dementia in elderly people. Magnetic Resonance Imaging (MRI) studies have demonstrated cerebral blood flow reduction in age-related white matter lesions, indicating that vascular alterations are ...
Meghdoot Mozumder, Jose M. Pozo, Santiago Coelho, Marina Costantini, Julie Simpson, J. Robin Highley, Paul G. Ince, Alejandro F. Frangi   +7 more
doaj   +1 more source