Results 11 to 20 of about 298,577 (257)

White Matter Lesions in Migraine [PDF]

The American Journal of Pathology, 2021
Migraine, the third most common disease worldwide, is a well-known independent risk factor for subclinical focal deep white matter lesions (WMLs), even in young and otherwise healthy individuals with no cardiovascular risk factors. These WMLs are more commonly seen in migraine patients with transient neurologic symptoms preceding their headaches, the ...
Katharina Eikermann-Haerter, Susie Y. Huang   +1 more
openaire   +2 more sources

Neurovascular-glymphatic dysfunction and white matter lesions [PDF]

GeroScience, 2021
Cerebral white matter lesions (WML) represent a spectrum of age-related structural changes that are identified as areas of white matter high signal intensity on brain magnetic resonance imaging (MRI). Preservation of white matter requires proper functioning of both the cerebrovascular and glymphatic systems.
Behnam Sabayan, Rudi G. J. Westendorp
openaire   +3 more sources

Software-based noise reduction in cranial magnetic resonance imaging: Influence on image quality. [PDF]

PLoS ONE, 2018
OBJECTIVES:To investigate acoustic noise reduction, image quality and white matter lesion detection rates of cranial magnetic resonance imaging (MRI) scans acquired with and without sequence-based acoustic noise reduction software.
Philipp Fuelkell, Soenke Langner, Nele Friedrich, Marie-Luise Kromrey, Christoph G Radosa, Ivan Platzek, Birger Mensel, Jens-Peter Kühn   +7 more
doaj   +1 more source

Brain White-Matter Lesions and Psychosis [PDF]

British Journal of Psychiatry, 1989
In a prospective study of late-life onset psychosis, five of the first 27 patients studied had extensive white-matter lesions demonstrated by MRI and/or CT. None of 60 age-matched psychiatrically healthy controls demonstrated such lesions. All five patients had a mild dementia and a frontal behavioural syndrome.
B L, Miller, I M, Lesser, K, Boone, M, Goldberg, E, Hill, M H, Miller, D F, Benson, M, Mehringer   +7 more
openaire   +4 more sources

Brain proteome‐wide association study linking‐genes in multiple sclerosis pathogenesis

Annals of Clinical and Translational Neurology, 2023
Objectives To identify genes that confer MS risk via the alteration of cis‐regulated protein abundance and verify their aberrant expression in human brain.
Tingting Jia, Yanni Ma, Fengqin Qin, Feng Han, Chengcheng Zhang   +4 more
doaj   +1 more source

White Matter Lesion Progression [PDF]

Stroke, 2015
Background and Purpose—White matter lesion (WML) progression on magnetic resonance imaging is related to cognitive decline and stroke, but its determinants besides baseline WML burden are largely unknown. Here, we estimated heritability of WML progression, and sought common genetic variants associated with WML progression in elderly participants from ...
Hofer, Edith, Cavalieri, Margherita, Bis, Joshua C., Decarli, Charles, Fornage, Myriam, Sigurdsson, Sigurdur, Srikanth, Velandai, Trompet, Stella, Verhaaren, Benjamin F.J., Wolf, Chris, Yang, Qiong, Adams, Hieab H.H., Amouyel, Philippe, Beiser, Alex, Buckley, Brendan M., Callisaya, Michele, Chauhan, Ganesh, de Craen, Anton J.M., Dufouil, Carole, van Duijn, Cornelia M., Ford, Ian, Freudenberger, Paul, Gottesman, Rebecca F., Gudnason, Vilmundur, Heiss, Gerardo, Hofman, Albert, Lumley, Thomas, Martinez, Oliver, Mazoyer, Bernard, Moran, Chris, Niessen, Wiro J., Phan, Thanh, Psaty, Bruce M., Satizabal, Claudia L., Sattar, Naveed, Schilling, Sabrina, Shibata, Dean K., Slagboom, P. Eline, Smith, Albert, Stott, David J., Taylor, Kent D., Thomson, Russell, Töglhofer, Anna M., Tzourio, Christophe, van Buchem, Mark, Wang, Jing, Westendorp, Rudi G.J., Gwen Windham, B., Vernooij, Meike W., Zijdenbos, Alex, Beare, Richard, Debette, Stéphanie, Ikram, M. Arfan, Jukema, J. Wouter, Launer, Lenore J., Longstreth, W. T., Mosley, Thomas H., Seshadri, Sudha, Schmidt, Helena, Schmidt, Reinhold   +59 more
openaire   +8 more sources

Automated segmentation of changes in FLAIR-hyperintense white matter lesions in multiple sclerosis on serial magnetic resonance imaging

NeuroImage: Clinical, 2019
Longitudinal analysis of white matter lesion changes on serial MRI has become an important parameter to study diseases with white-matter lesions. Here, we build on earlier work on cross-sectional lesion segmentation; we present a fully automatic pipeline
Paul Schmidt, Viola Pongratz, Pascal Küster, Dominik Meier, Jens Wuerfel, Carsten Lukas, Barbara Bellenberg, Frauke Zipp, Sergiu Groppa, Philipp G. Sämann, Frank Weber, Christian Gaser, Thomas Franke, Matthias Bussas, Jan Kirschke, Claus Zimmer, Bernhard Hemmer, Mark Mühlau   +17 more
doaj   +1 more source

Tissue transglutaminase in marmoset experimental multiple sclerosis: discrepancy between white and grey matter. [PDF]

PLoS ONE, 2014
Infiltration of leukocytes is a major pathological event in white matter lesion formation in the brain of multiple sclerosis (MS) patients. In grey matter lesions, less infiltration of these cells occur, but microglial activation is present.
Nathaly Espitia Pinzon, Esther Stroo, Bert A 't Hart, John G J M Bol, Benjamin Drukarch, Jan Bauer, Anne-Marie van Dam   +6 more
doaj   +1 more source

Damage to white matter bottlenecks contributes to language impairments after left hemispheric stroke

NeuroImage: Clinical, 2017
Damage to the white matter underlying the left posterior temporal lobe leads to deficits in multiple language functions. The posterior temporal white matter may correspond to a bottleneck where both dorsal and ventral language pathways are vulnerable to ...
Joseph C. Griffis, Rodolphe Nenert, Jane B. Allendorfer, Jerzy P. Szaflarski   +3 more
doaj   +1 more source

Damage to Association Fiber Tracts Impairs Recognition of the Facial Expression of Emotion [PDF]

, 2009
An array of cortical and subcortical structures have been implicated in the recognition of emotion from facial expressions. It remains unknown how these regions communicate as parts of a system to achieve recognition, but white matter tracts are likely ...
Adolphs, Ralph, Grabowski, Thomas, Mehta, Sonya, Philippi, Carissa L., Rudrauf, David   +4 more
core   +1 more source