Results 31 to 40 of about 298,577 (257)

Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination [PDF]

, 2017
[Background] The ability of oligodendrocyte progenitor cells (OPCs) to give raise to myelin forming cells during developmental myelination, normal adult physiology and post-lesion remyelination in white matter depends on factors which ...
Castro, Fernando de, Docagne, Fabian, Leonetti, Camille   +2 more
core   +1 more source

Synthetic double inversion recovery imaging in brain MRI: quantitative evaluation and feasibility of synthetic MRI and a comparison with conventional double inversion recovery and fluid-attenuated inversion recovery sequences

BMC Medical Imaging, 2022
Background and purpose Synthetic MR imaging (SyMRI) allows the reconstruction of various contrast images, including double inversion recovery (DIR), from a single scan.
Odgerel Zorigt, Takahito Nakajima, Yuka Kumasaka, Akiko Jingu, Yoshito Tsushima   +4 more
doaj   +1 more source

Tract Specific White Matter Lesion Load Affects White Matter Microstructure and Their Relationships With Functional Connectivity and Cognitive Decline

Frontiers in Aging Neuroscience, 2022
White matter hyperintensities (WMHs) are associated with cognitive decline. Assessing the effect of WMH on WM microstructural changes and its relationships with structural and functional connectivity to multiple cognitive domains are helpful to better ...
Tae Kim, Tae Kim, Howard J. Aizenstein, Beth E. Snitz, Yu Cheng, Yue-Fang Chang, Rebecca E. Roush, Theodore J. Huppert, Theodore J. Huppert, Annie Cohen, Jack Doman, James T. Becker   +11 more
doaj   +1 more source

Heat Transfer Model of Hyporthermic Intracarotid Infusion of Cold Saline for Stroke Therapy [PDF]

, 2006
A 3-dimensional hemispheric computational brain model is developed to simulate infusion of cold saline in the carotid arteries in terms of brain cooling for stroke therapy. The model is based on the Pennes bioheat equation, with four tissue layers: white
Konstas, Angelos-Aristeidis, Laine, Andrew F., Neimark, Matthew A., Pile-Spellman, John   +3 more
core   +2 more sources

Investigating White Matter Lesion Load, Intrinsic Functional Connectivity, and Cognitive Abilities in Older Adults [PDF]

, 2020
Changes to the while matter of the brain disrupt neural communication between spatially distributed brain regions and are associated with cognitive changes in later life.
Kantarovich, Karin
core  

Shallow vs deep learning architectures for white matter lesion segmentation in the early stages of multiple sclerosis [PDF]

, 2018
In this work, we present a comparison of a shallow and a deep learning architecture for the automated segmentation of white matter lesions in MR images of multiple sclerosis patients.
A Carass, D Garcia-Lorenzo, E Geremia, M Styner, MJ Fartaria, MJ Fartaria, MJ Fartaria, NJ Tustison, R Kikinis, S Klein, S Valverde, SB Kotsiantis, SM Smith, T Brosch   +13 more
core   +2 more sources

Grifolin attenuates white matter lesion in oxygen/glucose deprivation

Translational Neuroscience, 2017
The present study evaluates the effect of grifolin (GFL) in oxygen/glucose deprivation (OGD) induced white matter lesion. Injury induced with OGD was found to be significant at the 9th h of OGD induction and the effect of GFL on the proliferation of ...
Yanqin Ying, Jing Tang, Wei Chen, Nan Li
doaj   +1 more source

ADvanced IMage Algebra (ADIMA): a novel method for depicting multiple sclerosis lesion heterogeneity, as demonstrated by quantitative MRI. [PDF]

, 2013
There are modest correlations between multiple sclerosis (MS) disability and white matter lesion (WML) volumes, as measured by T2-weighted (T2w) magnetic resonance imaging (MRI) scans (T2-WML).
Altmann, DR, Anderson, VM, Chard, DT, Miller, DH, Schmierer, K, Tozer, DJ, Wheeler-Kingshott, CA, Yiannakas, MC   +7 more
core   +2 more sources

Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brain

Journal of Neuroinflammation, 2023
Background Ischemic stroke in white matter of the brain induces not only demyelination, but also neuroinflammation. Peripheral T lymphocytes, especially regulatory T cells (Tregs), are known to infiltrate into ischemic brain and play a crucial role in ...
Bin Xu, Hiroya Shimauchi-Ohtaki, Yuhei Yoshimoto, Tetsushi Sadakata, Yasuki Ishizaki   +4 more
doaj   +1 more source

Effects of Systolic Blood Pressure on Brain Integrity in Multiple Sclerosis

Frontiers in Neurology, 2018
Background: In MS patients, hypertension is associated with a delayed diagnosis and an increased risk of progression. Understanding the mechanisms of this association could potentially lead to improved prevention of disease progression.
Daiana E. Dossi, Hernán Chaves, Evelyn S. Heck, Sofía Rodriguez Murúa, Fernando Ventrice, Rohit Bakshi, Rohit Bakshi, Rohit Bakshi, Francisco J. Quintana, Francisco J. Quintana, Jorge Correale, Jorge Correale, Mauricio F. Farez   +12 more
doaj   +1 more source