Results 41 to 50 of about 298,577 (257)

Lesion distribution and substrate of white matter damage in myotonic dystrophy type 1: Comparison with multiple sclerosis

NeuroImage: Clinical, 2021
Myotonic Dystrophy type 1 (DM1) is an autosomal dominant condition caused by expansion of the CTG triplet repeats within the myotonic dystrophy protein of the kinase (DMPK) gene.
Sara Leddy, Laura Serra, Davide Esposito, Camilla Vizzotto, Giovanni Giulietti, Gabriella Silvestri, Antonio Petrucci, Giovanni Meola, Leonardo Lopiano, Mara Cercignani, Marco Bozzali   +10 more
doaj   +1 more source

Damage to fronto-parietal networks impairs motor imagery ability after stroke : a voxel-based lesion symptom mapping study [PDF]

, 2016
Background: mental practice with motor imagery has been shown to promote motor skill acquisition in healthy subjects and patients. Although lesions of the common motor imagery and motor execution neural network are expected to impair motor imagery ...
Oostra, Kristine M, Van Bladel, Anke, Vanhoonacker, Ann CL, Vingerhoets, Guy   +3 more
core   +2 more sources

Contrast-enhanced fluid-attenuated inversion-recovery (FLAIR) versus contrast-enhanced T1 MRI in the evaluation of intracranial tumors: A comparative study

Rwanda Medical Journal, 2022
INTRODUCTION: At most institutions, the favored contrast MR sequence is T1-weighted imaging (T1WI). However, lesion enhancement is occasionally inconspicuous on T1WI.
Q. A. Hassan
doaj   +2 more sources

Lesion Quantification Toolkit: A MATLAB software tool for estimating grey matter damage and white matter disconnections in patients with focal brain lesions

NeuroImage: Clinical, 2021
Lesion studies are an important tool for cognitive neuroscientists and neurologists. However, while brain lesion studies have traditionally aimed to localize neurological symptoms to specific anatomical loci, a growing body of evidence indicates that ...
Joseph C. Griffis, Nicholas V. Metcalf, Maurizio Corbetta, Gordon L. Shulman   +3 more
doaj   +1 more source

VIP-induced neuroprotection of the developing brain. [PDF]

, 2011
International audienceExcitotoxicity is a key molecular mechanism of perinatal brain damage and is associated with cerebral palsy and long term cognitive deficits.
Gressens, Pierre, Passemard, Sandrine, Schwendimann, Leslie, Sokolowska, Paulina   +3 more
core   +2 more sources

Blood Pressure Control in Aging Predicts Cerebral Atrophy Related to Small-Vessel White Matter Lesions

Frontiers in Aging Neuroscience, 2017
Cerebral small-vessel damage manifests as white matter hyperintensities and cerebral atrophy on brain MRI and is associated with aging, cognitive decline and dementia.
Kyle C. Kern, Clinton B. Wright, Kaitlin L. Bergfield, Kaitlin L. Bergfield, Megan C. Fitzhugh, Kewei Chen, Kewei Chen, Kewei Chen, James R. Moeller, Nooshin Nabizadeh, Mitchell S. V. Elkind, Ralph L. Sacco, Yaakov Stern, Yaakov Stern, Charles S. DeCarli, Gene E. Alexander, Gene E. Alexander, Gene E. Alexander, Gene E. Alexander   +18 more
doaj   +1 more source

BRAIN AND LESION VOLUMES CORRELATE WITH EDSS IN RELAPSING-REMITTING MULTIPLE SCLEROSIS. [PDF]

Journal of IMAB, 2015
Background: Demyelination and neurodegeneration are hallmarks of multiple sclerosis (MS). Axonal damage is considered to be the leading factor for persisting disability in the course of the disease. In different studies, expanded disability status scale (
Ivan Dimitrov, Radoslav Georgiev, Ara Kaprelyan, Nataliya Usheva, Margarita Grudkova, Kalina Drenska, Borislav Ivanov   +6 more
doaj   +1 more source

White matter injury restoration after stem cell administration in subcortical ischemic stroke [PDF]

, 2015
This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.[Introduction]: An animal model of subcortical ischemic stroke with white matter affectation was induced in rats by injection of endothelin-1.
C Matute, R Zhang, MP Goldberg, EG Sozmen, S Leu, O Lindvall, M Gutiérrez-Fernández, M Gutiérrez-Fernández, M Gutiérrez-Fernández, J Ramos-Cejudo, B Yang, JR Wiśniewski, S Martínez-Bartolomé, P Navarro, E Eden, GL Britton, DC Rogers, L Otero, L Otero, M Yanagisawa, EL Bailey, Q Jiang, Y Tanaka, J Ramos-Cejudo, JJ Jadasz, AH Crawford, JL Cheatwood   +26 more
core   +2 more sources

Epidemiology of White-Matter Lesions

International Psychogeriatrics, 2003
This is an overview of the prevalence of, and risk factors for white matter lesions in older persons. The prevalence of white matter lesions is high and increases with age. Most risk factors that have been examined in association with white matter lesions are similar to those for cardiovascular disease, including elevated blood pressure, diabetes ...
openaire   +3 more sources

The endocannabinoid 2-arachidonoylglycerol reduces lesion expansion and white matter damage after spinal cord injury

Neurobiology of Disease, 2010
A series of pathological events secondary to spinal cord injury (SCI) contribute to the spread of the damage, which aggravates neurological deficits. Here we report that a single dose of the neuroprotective endocannabinoid 2-arachidonoyl glycerol (2-AG ...
Angel Arevalo-Martin, Daniel Garcia-Ovejero, Eduardo Molina-Holgado   +2 more
doaj   +1 more source