Results 281 to 290 of about 704,012 (340)

SENP6 Maintains Mitochondrial Homeostasis by Regulating Mitochondrial Protein Import Through deSUMOylation of TOM40

Advanced Science, EarlyView.
SUMOylation regulates mitochondrial processes, but its impact on protein import remains unclear. TOM40 is identified, a mitochondrial outer membrane channel protein, as a substrate of deSUMOylase SENP6. TOM40 SUMOylation disrupts outer membrane complex assembly, inhibits protein import, and compromises mitochondrial homeostasis.
Liubing Hu, Jianshuang Li, Haolin Guo, Lei Su, Peina Dong, Juan Huang, Yanyan Liu, Xinjie Liu, Zhenhuan Luo, Wei Xiong, Zhenyu Ju, Qinghua Zhou, Hao Wang, Wenjun Wang   +13 more
wiley   +1 more source

Clonal hematopoiesis detection by simultaneous assessment of peripheral blood mononuclear cells, blood plasma, and saliva. [PDF]

J Clin Invest
Stewart CM, Parpart-Li S, White JR, Patel M, Artz O, Foote MB, Gedvilaite E, Lamendola-Essel MF, Gerber D, Bhattacharya R, Haseltine JM, Huberman K, Bolton KL, Levine RL, Diaz LA.   +14 more
europepmc   +1 more source

Molecular Mutation of the Coat Protein (CP) Gene in Alfalfa Mosaic Virus (AMV) and White Clover Mosaic Virus (WCMV) Combined Infection and the Role of the WCMV CP Gene When Infected with AMV

Yinge Chen, Qiaolan Liang, Liexin Wei, Xin Zhou, Siang Hui Lai   +4 more
openalex   +1 more source

Racial differences in endometrial cancer genomics and outcomes using UNCseq^TM targeted DNA sequencing. [PDF]

Gynecol Oncol Rep
Newton MA, Merker JD, Gong W, Patil S, Tan X, Cocoran DL, Pfefferle AD, Hayward MC, Broaddus R, Nichols HB, Olshan AF, Weissman B, Keku TO, Bae-Jump V.   +13 more
europepmc   +1 more source

Clinical Variation and Neuroimaging Patterns in Monozygotic Twins With Arrested X-Linked Adrenoleukodystrophy: A Case Report. [PDF]

Cureus
Leon TA, Nelson SM, Gilman A, Kluesner J, Williams JP.   +4 more
europepmc   +1 more source

Clinical profile, atrophy and inheritance patterns of pathogenic MAPT gene mutations in Frontotemporal dementia detected using whole exome sequencing: a single-center first report from India. [PDF]

BMC Neurol
Ramakrishnan S, Arshad F, Keerthana BS, Bosco S, Gokul Pon A, Ganaraja VH, Madhusudhan D, Mahima R, Arunachal G, Kulanthaivelu K, Alladi S.   +10 more
europepmc   +1 more source

Respiration defects limit serine synthesis required for lung cancer growth and survival. [PDF]

Nat Commun
Cararo Lopes E, Shi F, Sawant A, Ibrahim M, Gomez-Jenkins M, Hu Z, Manchiraju P, Bhatt V, Wang W, Hinrichs CS, Wallace DC, Su X, Rabinowitz JD, Chan CS, Guo JY, Ganesan S, Lattime EC, White E.   +17 more
europepmc   +1 more source

Genetic and clinical features of hereditary transthyretin amyloidosis: a decade of experience at a Japanese referral center. [PDF]

Orphanet J Rare Dis
Nomura T, Misumi Y, Tasaki M, Yamakawa S, Taguchi T, Obayashi K, Yamashita T, Ando Y, Ueda M.   +8 more
europepmc   +1 more source