Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley +1 more source
Association between metabolic syndrome and hearing loss: The mediating role of retinol - A cross-sectional analysis of NHANES 2007 to 2018 (excluding 2013-2014). [PDF]
Mao L, Pan Z, Hu W, Dai H, Chen X.
europepmc +1 more source
Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou +12 more
wiley +1 more source
Deep reinforcement learning-based reversible medical image encryption framework for secure IoMT environments. [PDF]
Mahalakshmi K, Nagarajan S.
europepmc +1 more source
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu +14 more
wiley +1 more source
Dissociable effects of element-lifetime and stimulus-duration on local and global motion processing: An equivalent noise study. [PDF]
Vivekanandan B, Dakin SC.
europepmc +1 more source
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud +12 more
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Analysis and Prediction of the Earthquake Frequency Sequence in the Anninghe Fault Zone Based on the SARIMA Model. [PDF]
Fang X, Xue Y.
europepmc +1 more source
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li +14 more
wiley +1 more source
Generation of Probabilistic Bits by Exploiting Orthogonal Spin Currents in Magnetic Trilayers
Fe/Ti/CoFeB trilayers generate orthogonal spin currents that drive stochastic spin–orbit‐torque switching for probabilistic‐bit operation. The switching probability is continuously controlled by the in‐plane magnetic field and drive current, enabling tunable random bit generation.
Donghyeon Han +17 more
wiley +1 more source

