Results 31 to 40 of about 4,659,902 (256)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

White Paper on Early Critical Care Services in Low Resource Settings

Annals of Global Health, 2021
This White Paper has been formally accepted for support by the International Federation for Emergency Medicine (IFEM) and by the World Federation of Intensive and Critical Care (WFICC), put forth by a multi-specialty group of intensivists and emergency ...
Lia I. Losonczy, Alfred Papali, Sean Kivlehan, Emilie J. Calvello Hynes, Georgina Calderon, Adam Laytin, Vanessa Moll, Ahmed Al Hazmi, Mohammed Alsabri, Diptesh Aryal, Vincent Atua, Torben Becker, Nicole Benzoni, Enrico Dippenaar, Edrist Duneant, Biruk Girma, Naomi George, Preeti Gupta, Michael Jaung, Bonaventure Hollong, Diulu Kabongo, Rebecca J. Kruisselbrink, Dennis Lee, Augusto Maldonado, Jesse May, Maxwell Osei-Ampofo, Yasein Omer Osman, Christian Owoo, Shada A. Rouhani, Hendry Sawe, Daniel Schnorr, Gentle S. Shrestha, Aparajita Sohoni, Menbeu Sultan, Andrea G. Tenner, Hanan Yusuf, Neill K. Adhikari, Srinvas Murthy, Niranjan Kissoon, John Marshall, Abdo Khoury, Abdelouahab Bellou, Lee Wallis, Teri Reynolds   +43 more
doaj   +1 more source

Light Sterile Neutrinos: A White Paper [PDF]

, 2012
This white paper addresses the hypothesis of light sterile neutrinos based on recent anomalies observed in neutrino experiments and the latest astrophysical ...
Abazajian, K. N., Acero, M. A., Agarwalla, S. K., Aguilar-Arevalo, A. A., Albright, C. H., Antusch, S., Arguelles, C. A., Balantekin, A. B., Barenboim, G., Barger, V., Berguno, D. Bravo, Bernardini, P., Bezrukov, F., Bjaelde, O. E., Bogacz, S. A., Bowden, N. S., Boyarsky, A., Bravar, A., Brice, S. J., Bross, A. D., Caccianiga, B., Cavanna, F., Chun, E. J., Cleveland, B. T., Collin, A. P., Coloma, P., Conrad, J. M., Cribier, M., Cucoanes, A. S., D'Olivo, J. C., Das, S., de Gouvea, A., Derbin, A. V., Dharmapalan, R., Diaz, J. S., Ding, X. J., Djurcic, Z., Donini, A., Duchesneau, D., Ejiri, H., Elliott, S. R., Ernst, D. J., Esmaili, A., Evans, J. J., Fernandez-Martinez, E., Figueroa-Feliciano, E., Fleming, B. T., Formaggio, J. A., Franco, D., Gaffiot, J., Gandhi, R., Gao, Y., Garvey, G. T., Gavrin, V. N., Ghoshal, P., Gibin, D., Giunti, C., Gninenko, S. N., Gorbachev, V. V., Gorbunov, D. S., Guenette, R., Guglielmi, A., Halzen, F., Hamann, J., Hannestad, S., Haxton, W., Heeger, K. M., Henning, R., Hernandez, P., Huber, P., Huelsnitz, W., Ianni, A., Ibragimova, T. V., Karadzhov, Y., Karagiorgi, G., Keefer, G., Kim, Y. D., Kopp, J., Kornoukhov, V. N., Kusenko, A., Kyberd, P., Langacker, P., Lasserre, Th., Laveder, M., Letourneau, A., Lhuillier, D., Li, Y. F., Lindner, M., Link, J. M., Littlejohn, B. L., Lombardi, P., Long, K., Lopez-Pavon, J., Louis, W. C., Ludhova, L., Lykken, J. D., Machado, P. A. N., Maltoni, M., Mann, W. A., Marfatia, D., Mariani, C., Matveev, V. A., Mavromatos, N. E., Melchiorri, A., Meloni, D., Mena, O., Mention, G., Merle, A., Meroni, E., Mezzetto, M., Mills, G. B., Minic, D., Miramonti, L., Mohapatra, D., Mohapatra, R. N., Montanari, C., Mori, Y., Mueller, Th. A., Mumm, H. P., Muratova, V., Nelson, A. E., Nico, J. S., Noah, E., Nowak, J., Obolensky, M., Pakvasa, S., Palamara, O., Pallavicini, M., Pascoli, S., Patrizii, L., Pavlovic, Z., Peres, O. L. G., Pessard, H., Pietropaolo, F., Pitt, M. L., Popovic, M., Pradler, J., Ranucci, G., Ray, H., Razzaque, S., Rebel, B., Robertson, R. G. H., Rodejohann, W., Rountree, S. D., Rubbia, C., Ruchayskiy, O., Sala, P. R., Scholberg, K., Schwetz, T., Shaevitz, M. H., Shaposhnikov, M., Shrock, R., Simone, S., Skorokhvatov, M., Smirnov, O. Yu., Sorel, M., Sousa, A., Spergel, D. N., Spitz, J., Stanco, L., Stancu, I., Suzuki, A., Takeuchi, T., Tamborra, I., Tang, J., Testera, G., Tian, X. C., Tonazzo, A., Tunnell, C. D., Van de Water, R. G., Verde, L., Veretenkin, E. P., Vignoli, C., Vivier, M., Vogelaar, R. B., Wascko, M. O., Wilkerson, J. F., Winter, W., Wong, Y. Y. Y., Yanagida, T. T., Yasuda, O., Yeh, M., Yermia, F., Yokley, Z. W., Zeller, G. P., Zhan, L., Zhang, H.   +186 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

White Paper on Research Data Service Discoverability

Publications, 2016
This White Paper reports the outcome of a Workshop on “Research Data Service Discoverability” held in the island of Santorini (GR) on 21–22 April 2016 and organized in the context of the EU funded Project “RDA-E3”.
Costantino Thanos, Friederike Klan, Kyriakos Kritikos, Leonardo Candela   +3 more
doaj   +1 more source

White Paper: Measuring the Neutrino Mass Hierarchy [PDF]

, 2013
This white paper is a condensation of a report by a committee appointed jointly by the Nuclear Science and Physics Divisions at Lawrence Berkeley National Laboratory (LBNL).
Cahn, R. N., Dwyer, D. A., Freedman, S. J., Gann, G. D. Orebi, Haxton, W. C., Kadel, R. W., Kolomensky, Yu. G., Luk, K. B., McDonald, P., Poon, A. W. P.   +9 more
core   +1 more source

6G White Paper on Machine Learning in Wireless Communication Networks

, 2020
The focus of this white paper is on machine learning (ML) in wireless communications. 6G wireless communication networks will be the backbone of the digital transformation of societies by providing ubiquitous, reliable, and near-instant wireless ...
Abbas, Robert, Ahmad, Ijaz, Ali, Samad, Amuru, Saidhiraj, Bhadauria, Shubhangi, Bhatia, Vimal, Capobianco, Michele, Chang, Kapseok, Chen, Mingzhe, Chu, Thi My Chinh, Claes, Maelick, Girnyk, Maksym, Huusko, Jyrki, Karvonen, Teemu, Malik, Hassan, Mei, Kai, Mitra, Rangeet, Rajatheva, Nandana, Saad, Walid, Shao, Baohua, Shiri, Hamid, Sliwa, Benjamin, Steinbach, Daniel, Suutala, Jaakko, Wietfeld, Christian, Yu, Guanghui, Zepernick, Hans-Jürgen   +26 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Snowmass white paper: beyond the standard model effects on neutrino flavor

European Physical Journal C: Particles and Fields, 2023
Neutrinos are one of the most promising messengers for signals of new physics Beyond the Standard Model (BSM). On the theoretical side, their elusive nature, combined with their unknown mass mechanism, seems to indicate that the neutrino sector is indeed
C. A. Argüelles, G. Barenboim, M. Bustamante, P. Coloma, P. B. Denton, I. Esteban, Y. Farzan, E. Fernández Martínez, D. V. Forero, A. M. Gago, T. Katori, R. Lehnert, M. Ross-Lonergan, A. M. Suliga, Z. Tabrizi, L. Anchordoqui, K. Chakraborty, J. Conrad, A. Das, C. S. Fong, B. R. Littlejohn, M. Maltoni, D. Parno, J. Spitz, J. Tang, S. Wissel   +25 more
doaj   +1 more source