Results 31 to 40 of about 7,367,341 (295)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Racial Undertones on Violence and Human Bodies: White Migrants' Online Epistemologies of Insecurity and Discomfort in Post-Apartheid South Africa

International Journal of Critical Diversity Studies, 2019
Violence and insecurity in post-apartheid South Africa are recurrent themes in online messages by white South Africans who have either migrated or wish to leave the country.
Primus Tazanu
doaj   +1 more source

Implications of institutional racism in the therapeutic itinerary of people with chronic renal failure

Investigación y Educación en Enfermería, 2020
Objective. To understand the implications of institutional racism in the therapeutic itinerary of patients with chronic renal failure (CRF) in the search for diagnosis and treatment of the disease. Methods.
Ricardo Bruno Santos Ferreira, Climene Laura de Camargo, Maria Inês da Silva Barbosa, Maria Lúcia Silva Servo, Marcia Maria Carneiro Oliveira, Juliana Alves Leite Leal   +5 more
doaj   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

The Residential Segregation of the Middle Eastern and North African and South Asian Populations from the White Population in U.S. Metropolitan Areas, 2012–2016

Social Sciences
We examine the residential segregation of the Middle Eastern and North African (MENA) population, South and East Asian people, and Black from white people in the U.S.
Sevsem Cicek-Okay, Samantha Friedman
doaj   +1 more source

We Need to Talk about White People

Multicultural Perspectives, 2019
On both sides of the Atlantic Ocean the interests, fears, and voices of “ordinary” White people have become a prominent part of mainstream political and educational debate.
D. Gillborn
semanticscholar   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

The role of racial group solidarity in intergroup relations between Black-White multiracial and Black monoracial people

Scientific Reports
Across two studies, we examined intergroup relations between Black-White multiracial and Black monoracial people in the U.S. Study 1 showed that Black-White multiracial participants reported more solidarity with Black than White people, but less ...
Nadia Vossoughi, Nour S. Kteily, Steven O. Roberts, Rachel D. Fine, Arnold K. Ho   +4 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Varying circumstances surrounding opioid toxicity deaths across ethno-racial groups in Ontario, Canada: a population-based descriptive cross-sectional study

BMJ Public Health
Introduction The North American toxic drug crisis has been framed as an epidemic primarily affecting white people. However, evidence suggests that deaths are rising among racialised people.
Tara Gomes, Mina Tadrous, Sophie A Kitchen, Frank Crichlow, Tonya J Campbell, Cynthia Damba, Colin H Johnson, Ashley Smoke   +7 more
doaj   +1 more source