Results 31 to 40 of about 161,335 (256)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Expert consensus on the prevention and treatment of enamel demineralization in orthodontic treatment

open access: yesInternational Journal of Oral Science
s Enamel demineralization, the formation of white spot lesions, is a common issue in clinical orthodontic treatment. The appearance of white spot lesions not only affects the texture and health of dental hard tissues but also impacts the health and ...
Lunguo Xia   +31 more
doaj   +1 more source

Assessment of White Spot Lesions and In-Vivo Evaluation of the Effect of CPP-ACP on White Spot Lesions in Permanent Molars of Children [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: As hindrance of remineralisation process occurs during orthodontic therapy resulting in decalcification of enamel because number of plaque retention sites increases due to banding and bonding of appliances to teeth.
Deepti Munjal   +4 more
doaj   +1 more source

Evaluation of Spinach Cultivars for Resistance to Stemphylium Leaf Spot (Stemphylium vesicarium) and White Rust (Albugo occidentalis)

open access: yesHortScience, 2023
Stemphylium leaf spot, caused by Stemphylium vesicarium, and white rust, caused by Albugo occidentalis, can cause significant losses in spinach production.
Kayla A. Spawton   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Penatalaksanaan white spot lesion setelah perawatan ortodontik dengan teknik resin infiltration

Management of white spot lesion after orthodontic treatment with resin infiltration technique

open access: yesJurnal Kedokteran Gigi Universitas Padjadjaran, 2019
Pendahuluan: White spot lesion merupakan porositas-porositas di bawah permukaan email yang disebabkan oleh proses demineralisasi. Proses ini dapat terjadi karena adanya efek samping iatrogenik dari perawatan ortodontik melalui akumulai plak dalam jangka ...
Desneli Desneli, Anna Muryani
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Caries infiltration of noncavitated white spot lesions: A novel approach for immediate esthetic improvement

open access: yesContemporary Clinical Dentistry, 2012
The earliest evidence of demineralization on the smooth enamel surface of a crown is a white spot lesion. The conventional treatment of these white spot lesions includes topical fluoride application, iamproving the oral hygiene, and use of remineralizing
Neeraj Gugnani   +3 more
doaj   +1 more source

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