Results 121 to 130 of about 3,133,505 (240)

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Effect of Different Professional Prophylaxis Systems in Induced White Spot Lesions: An in Vitro Study

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To evaluate the effect of different prophylaxis systems on the surface of sound enamel and in induced white spot lesions using confocal microscopy analysis. Material and Methods: 40 specimens were obtained from sound premolars, and the buccal
Thaís Citolino Barbosa Seno, Larissa Oliveira Minchillo, Patrícia Gatón-Hernández, Renata Zoraida Rizental Delgado, Regina Guenka Palma-Dibb, Juliana Jendiroba Faraoni, Raquel Assed Bezerra Segato, Léa Assed Bezera da Silva, Ana Zilda Nazar Bergamo, Paulo Nelson-Filho   +9 more
doaj  

Comparison of three orthodontic bonding systems in white spot lesion development: a randomized clinical trial. [PDF]

Angle Orthod, 2023
Horan OGA, Al-Khateeb SN.
europepmc   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

On the epidemiology and evolution of white spot syndrome virus of shrimp [PDF]

, 2010
WSSV causes a devastating disease in shrimp aquaculture that has spread worldwide and probably increased in virulence over time. Understanding WSSV epidemiology and evolution is therefore important for developing novel intervention and management ...
Bui Thi Minh Dieu
core  

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Presumed solitary circumscribed retinal astrocytic proliferation: a lesion that can regress

International Medical Case Reports Journal, 2019
Víctor Manuel Asensio-SánchezOphthalmology Department, Clinical University Hospital of Valladolid, Valladolid, SpainAbstract: A 56-year-old woman had an yellow-white retinal lesion superior to the optic disc.
Asensio-Sánchez VM
doaj  

Letter from Herbert White

, 2012
Letters from Herbert White to his ...
White, Herbert Martin
core  

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source