Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong +8 more
wiley +1 more source
Remineralising efficacy of bioactive glass and casein phosphopeptide amorphous calcium phosphate in white spot lesions or early enamel caries: A systematic review of randomised controlled trials. [PDF]
Mishra A, Sharan J, Sivakumar I.
europepmc +1 more source
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong +14 more
wiley +1 more source
Impact of adhesive layer addition on the optical properties of remineralized white spot lesions. [PDF]
Zotti F +3 more
europepmc +1 more source
White spot lesions ja oikomishoito
White spot lesions (WSLs) are early signs of enamel demineralisation that develop with increased frequency during and after fixed orthodontic treatment, posing both aesthetic and clinical concerns for patients. This descriptive literature review examines
Varjonen, Severi
core
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan +5 more
wiley +1 more source
Preparation and Evaluation of the Remineralization Effect of a Dental Varnish Containing Casein Phosphopeptide-Amorphous Calcium Phosphate with Fluoride (Cpp-Acpf) on White Spot Lesions of Permanent Teeth: An In Vitro Study. [PDF]
Uriat S +3 more
europepmc +1 more source
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley +1 more source
Chitosan-arginine/amorphous calcium phosphate nanoparticles-containing orthodontic cement: antibacterial and remineralization strategies against enamel white spot lesions. [PDF]
An J, Dai Z, Xu H.
europepmc +1 more source
Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang +9 more
wiley +1 more source

