Results 131 to 140 of about 533,338 (347)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Decolouring bloodmeal: Consumption and potential recycling of peracetic acid [PDF]
, 2012 A method of deodorizing and decolouring bloodmeal using an equilibrium mixture of peracetic acid, hydrogen peroxide, acetic acid and water has been developed to improve its marketability as a source of protein for bioplastics.
Hicks, Talia +3 more
core +1 more source
Effect of White Clover (Trifolium repens L.) Undersowing Cultivation and Nitrogen Fertilization on Weed Infestation, Biomass Yield and Its Component, Content and Uptake of Macroelements of Willow (Salix viminalis L.) [PDF]
, 2021 Waldemar Helios
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The Double-Edged Nature of Whiteness for Multiracial People with White Ancestry in the US and UK
GenealogyThe privileges of Whiteness have been theorized and debated for some decades. Because White privilege has been manifested, historically, in myriad forms, it has been possible to treat the privileges of Whiteness as a given, even when its changing ...
Miri Song
doaj +1 more source
Feminine Purity and Masculine Revenge-Seeking In \u3ci\u3eTaken\u3c/i\u3e (2008) [PDF]
, 2014 The 2008 film Taken depicts the murderous rampage of an ex-CIA agent seeking to recover his teenage daughter from foreign sex traffickers. I argue that Taken articulates a demand for a white male protector to serve as both guardian and avenger of white ...
Kelly, Casey R.
core +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
HeliyonThis article sets out investigate the interrelationships between native speakerism, Whiteness, ethnicity and appearance in the TESOL context. It explores whether Whiteness plays a part in TESOL teachers' recruitment and job opportunities when employers ...
Muneer Hezam Alqahtani
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source