Results 81 to 90 of about 3,641,455 (278)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Drying and color kinetics of decorticated queen pineapple (Ananas comosus Linn.) fiber bleached with hydrogen peroxide solution

Research in Agricultural Engineering
The drying and colour kinetics of H2O2-bleached pineapple fibres were studied to determine an optimum drying condition and appropriate drying and colour kinetic models. The experiments were conducted under drying air temperatures of 40, 50 and 60 ºC, air
Roger Jay Lamadrid De Vela, Arnold Recidocruz Elepano   +1 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Laundering-induced alterations in color and whiteness of cotton-based fabrics: A comparative analysis of powder and liquid detergents [PDF]

Tekstilna industrija
Maintaining the intrinsic chromatic integrity of dyed textiles is paramount for optimizing product lifecycle value, enhancing consumer perception, and advancing sustainable material stewardship.
Toshikj Emilija, Mangovska Biljana
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Hot air aging behavior of rubber latex foams materials with different natural rubber latex content

Hecheng xiangjiao gongye, 2021
Five kinds of rubber latex foams with different natural rubber latex content were studied by the accelerated hot air aging method, and the aging degree and aging rate were characterized by aging kinetic model and several performance parameters, such as ...
CHEN Chen1; HUANG Dong-mei1; ZHANG Xiang-yu2; WANG ying2; WANG Wu-kang2
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Subjective and objective/machine evaluation of wool luster in Magra sheep vis-a-vis wool grading and animal selection

Journal of Natural Fibers, 2019
Wool of Magra sheep in India is well-known for its fiber quality and luster. In the present study, subjective and objective luster grading wool clips and its association with fiber diameter was done.
Ajay Kumar, R. K. Sawal, H. K. Narula, S. Kumar, Rajiv Kumar   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source