Results 121 to 130 of about 10,594 (308)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Editorial: Different pathways into critical whiteness studies [PDF]

open access: yes, 2012
This special issue explores the complexities of critical whiteness studies methodologies. We decided upon critical whiteness studies (CWS) as our nodal point for this special issue since we believe whiteness often stays unchallenged as un-articulated and
Pedersen, Linda, Samaluk, Barbara
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

On Whiteness: Current Debates in Australian Studies

open access: yes, 2011
Whiteness Studies in Australia arguably began as a reflection on the worry, concern and fear of ordinary Australians for border control. While this highly ideological fantasy was orchestrated during the 1990s by the Hansonites and John Howard, it ...
Russo, KATHERINE ELIZABETH   +4 more
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Ablaze: The 1849 White Supremacist Attack on the Pendleton Post Office

open access: yesSouthern Spaces, 2022
In 1849 a mob of white supremacists eager to seize anti-slavery mailings attacked the US Post Office in Pendleton, South Carolina. They burned leaflets and letters in a bonfire on the village green to make clear their stance against incendiary ideas ...
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Neoliberalism, Global “Whiteness,” and the Desire for Adoptive Invisibility in US Parental Memoirs of Eastern European Adoption

open access: yesJournal of Transnational American Studies, 2011
<p>This essay explores the recent surge in US parental memoirs of adoption from Russia and Ukraine. This analysis of the most influential works speculatively highlights underexamined connections between the US media focus on adoption failures and ...
Claudia Sadowski-Smith
doaj  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Editorial: Law, race and whiteness

open access: yes, 2008
The contributions to this special issue of the ACRAWSA e-journal critically interrogate the interface of Anglo- Australian law and legal systems, race and whiteness.
Luker, Trish, Nielsen, Jennifer
core  

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