Results 31 to 40 of about 9,665 (128)

Mouse Model of Heart Failure With Preserved Ejection Fraction Driven by Hyperlipidemia and Enhanced Cardiac Low‐Density Lipoprotein Receptor Expression

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The pathways of diastolic dysfunction and heart failure with preserved ejection fraction driven by lipotoxicity with metabolic syndrome are incompletely understood.
Monique Williams, Jose Manuel Condor Capcha, Camila Iansen Irion, Grace Seo, Guerline Lambert, Ali Kamiar, Keyvan Yousefi, Rosemeire Kanashiro‐Takeuchi, Lauro Takeuchi, Ali G. Saad, Armando Mendez, Keith A. Webster, Jeffrey J. Goldberger, Joshua M. Hare, Lina A. Shehadeh   +14 more
doaj   +1 more source

Measurement of Airway Responsiveness on Vigil and Unrestrained Mouse

Bio-Protocol, 2013
Airway hyperresponsiveness to methacholine is an important characteristic of asthma. This protocol describes how to measure airway response to methacholine in vigil and unrestraint mouse.
François Daubeuf, Laurent Reber, Nelly Frossard   +2 more
doaj   +1 more source

Invasive and noninvasive methods for studying pulmonary function in mice

Respiratory Research, 2007
The widespread use of genetically altered mouse models of experimental asthma has stimulated the development of lung function techniques in vivo to characterize the functional results of genetic manipulations.
Braun Armin, Taube Christian, Glaab Thomas, Mitzner Wayne   +3 more
doaj   +1 more source

Measurement of the Total Lung Volume Using an Adjusted Single-Breath Helium Dilution Method in Patients With Obstructive Lung Disease

Frontiers in Medicine, 2021
Background: Whole-body plethysmography (WBP) is the gold standard for measuring lung volume, but its clinical application is limited as it requires expensive equipment and is not simple to use.
Qing Liu, Lingxiao Zhou, Peiling Feng, Jinkai Liu, Bin Shen, Lili Huang, Yingying Wang, Yimin Zou, Yang Xia, Gang Huang   +9 more
doaj   +1 more source

Assessment of respiratory involvement in children with mucoplysaccharidosis using pulmonary function tests

Egyptian Journal of Medical Human Genetics, 2014
Background: Mucopolysaccharidosis (MPS) are classified into seven clinical types based on eleven known lysosomal enzyme deficiencies of glycosaminoglycan (GAG) metabolism.
Mona M. El Falaki, Marian Y. Girgis, Aliaa A. Ali, Mohamed A. Elmonem, Heba M. Ismail   +4 more
doaj   +1 more source

The abdominal circulatory pump. [PDF]

PLoS ONE, 2009
Blood in the splanchnic vasculature can be transferred to the extremities. We quantified such blood shifts in normal subjects by measuring trunk volume by optoelectronic plethysmography, simultaneously with changes in body volume by whole body ...
Andrea Aliverti, Dario Bovio, Irene Fullin, Raffaele L Dellacà, Antonella Lo Mauro, Antonio Pedotti, Peter T Macklem   +6 more
doaj   +1 more source

Positive correlation of airway resistance and serum asymmetric dimethylarginine (ADMA) in bronchial asthma patients lacking evidence for systemic inflammation

Allergy, Asthma & Clinical Immunology, 2018
Background Contribution of nitric-oxide (NO) pathway to the pathogenesis of bronchial asthma (asthma) is ambiguous as NO may confer both protective and detrimental effects depending on the NO synthase (NOS) isoforms, tissue compartments and underlying ...
Gabor Tajti, Csaba Papp, Laszlo Kardos, Sandor Keki, Krisztian Pak, Magdolna Emma Szilasi, Rudolf Gesztelyi, Angela Mikaczo, Andrea Fodor, Maria Szilasi, Judit Zsuga   +10 more
doaj   +1 more source

Evaluation of the Sensory Stimulation Intensity of Representative Spicy Flavor Substances Using Whole-Body Plethysmography [PDF]

Shipin Kexue
This study aimed to investigate the impact of spicy stimuli on the respiratory status of rats inhaling aerosols of spicy substances. The intensity of spicy stimuli was characterized by examining changes in multiple respiratory function indicators ...
LIU Fuqiang, GUO Lulu, MAO Jian, CHAI Guobi, ZHANG Qidong, ZHANG Wenjuan, LIU Xingyu, ZHANG Tianbing, XIE Jiqing, XIE Jianping
doaj   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao, Xudong Yu, Ziqian Shang, Mengyao Tan, Xie Huang, Zaizhi Du, Xiaojiao Wang, Xinrui Yang, Ximei Luo, Weidong Wang, Rong Li, Shenglin Luo   +11 more
wiley   +1 more source

An open-source tool for automated analysis of breathing behaviors in common marmosets and rodents

eLife, 2022
The respiratory system maintains homeostatic levels of oxygen (O2) and carbon dioxide (CO2) in the body through rapid and efficient regulation of breathing frequency and depth (tidal volume).
Mitchell Bishop, Maximilian Weinhold, Ariana Z Turk, Afuh Adeck, Shahriar SheikhBahaei   +4 more
doaj   +1 more source