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The Safety of Acellular Pertussis Vaccine vs Whole-Cell Pertussis Vaccine
Archives of Pediatrics & Adolescent Medicine, 1996To determine the impact of the introduction of acellular pertussis vaccine for the fourth and fifth doses of the diphtheria and tetanus toxoids and pertussis vaccine series in children on rates of reported vaccine-associated adverse events in the United States.Analysis of postmarketing vaccine adverse event data from the Vaccine Adverse Event Reporting
S, Rosenthal, R, Chen, S, Hadler
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Bordetella Pertussis Whole Cell Vaccines–Efficacy and Toxicity
Acta Paediatrica, 1984The literature concerning efficacy and side effects of pertussis vaccines is reviewed. With few exceptions, most vaccines induce a protective immunity lasting for 2 to 5 years. The large‐scale use of pertussis vaccines has markedly contributed to the decrease in pertussis morbidity in small children but in some countries the incidence has increased in ...
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Vaccination against Pertussis in the era of acellular and whole-cell vaccines
Medical Research ArchivesPertussis in a highly infectious respiratory disease, and even though vaccination has been globally implemented since the 1940s, we are far from elimination, and even still suffering from many outbreaks throughout the world. This comprehensive review is tailored primarily for clinicians and healthcare practitioners, aiming to deepen their insights ...
Enrique Cruz +10 more
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The effectiveness of whole-cell pertussis vaccines.
Developments in biological standardization, 1997The acellular pertussis vaccine efficacy trials revealed significant facts concerning the whole cell vaccines used as controls. At least three whole-cell vaccines were shown to have considerable efficacy, and in fact superior efficacy to the acellular vaccines to which they were compared.
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The History of Pertussis Vaccination: From Whole-Cell to Subunit Vaccines
2011A review of all studies and trials cannot be made in this context, but two sources are recommended, i.e., Whooping cough by Joseph E. Lapin [1] and a review by Fine and Clarkson [2]. In the early years of the twentieth century, attempts were made to develop whole-cell vaccines, but for these early studies, the current definition of vaccination may not ...
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Autologous whole-cell cancer vaccination: Cryogenic silicified vaccines
Matter, 2022Yun Chen, Sishi Guo, Wei Zhu
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