Results 31 to 40 of about 12,108,613 (278)

Developing Whole Leaders for the Whole World [PDF]

, 2015
How do we holistically develop leaders with the capacity and character to tackle the most pressing moral challenges in our modern world? While it may be easier to focus on one thing such as strengths, experiences, or mentors, the reality is that ...
McKenna, Robert, Wenzel, Kira K.
core   +2 more sources

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt, Elisabeth T. Tracy, Anghela Paredes, Catherine Beckhorn, Harold J. Leraas, Joseph Fusco, Katlyn G. McKay, Nelly‐Ange T. Kontchou, Zachary J. Kastenberg, David W. Hoyt, Jonathan Roach, Emily K. Myers, Nicholas G. Cost, Bhargava Mullapudi, Charles R. Marchese, Amanda R. Jensen, Timothy B. Lautz, Michela Carter, Roshni Dasgupta, John Lundstedt, Joseph G. Brungardt, Lindsay Talbot, Andrew M. Davidoff, Andrew J. Murphy, Jennifer H. Aldrink, Sara Mansfield, Nelson Piche, Annie Le‐Nguyen, Dave R. Lal, Brian T. Craig, Jennifer M. Schuh, Barrett P. Cromeens, Sindhu Mannava, Shannon Castle, Adriana Lopez, Kelsey Mello, Joshua Short, Robin T. Petroze, Shay Rajaval, Grace R. Thompson, Peter Mattei, David H. Rothstein, Elizabeth Fialkowski, Kathryn Fowler, Nathan Martchenke, Barrie S. Rich, Richard D. Glick, Erin G. Brown, Kathleen Doyle, Paige Abril, Natashia Seemann, Jacob Davidson, Claire A. Wilson, Hau D. Le, Devashish Joshi, Michael Stellon, Tamer Ahmed, Alexandra Dimmer, Peter F. Ehrlich, Maya Hammoud, Keyonna Williams, Christa N. Grant, Merit Gorgy, Stephanie F. Polites, Julia Debertin, Danielle B. Cameron, Alyssa Stetson, Eugene S. Kim, William G. Lee, Aaron Barkhordar, Mary Austin, Brian A. Coakley, Anastasia Kahan, Joseph T. Murphy, Michael Pitonak, Chloé Boehmer, Marcus M. Malek   +76 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Interaction of Gamma-Aminobutyric Acid and Ca²⁺ on Phenolic Compounds Bioaccumulation in Soybean Sprouts under NaCl Stress

Plants, 2022
NaCl stress can enhance the accumulation of phenolic compounds in soybean during germination. In the present study, effects of gamma-aminobutyric acid (GABA) and Ca2+ on the biosynthesis of phenolic compounds in soybean sprouts germinated with NaCl ...
Chong Xie, Maomao Sun, Pei Wang, Runqiang Yang   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Ischial osteochondroma as an unusual source of pregnancy-related sciatic pain: a case report

Chiropractic & Manual Therapies, 2022
Background While most cases of sciatica result from degenerative conditions of the low back, some cases result from conditions of the hip and pelvic region. Sciatica developing in relation to pregnancy or labor also presents unique considerations.
Robert J. Trager, Sarah E. Prosak, Patrick J. Getty, Richard L. Barger, Shahrazad T. Saab, Jeffery A. Dusek   +5 more
doaj   +1 more source

Whole issue

Language Value, 2011
Table of Contents From the editors Begoña Bellés-Fortuño Articles  Multimodal literacy in academic environments: PowerPoint as a motivational genre. Stefania Consonni PowerPoint Presentations in the classroom: Re-evaluating the genre. Larissa d’Angelo Listening with your eyes: Multimodal approaches to art appreciation in primary school.
openaire   +17 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Yapay Nesne Ontolojisinin İmkânı

Felsefe Dünyası
Belli bir amacı yerine getirmek için insan eliyle maddenin modifiye edilmesiyle bilinçli bir biçimde yapılmış nesneler olarak tanımlanan yapay nesneler, Aristoteles’in doğal olarak var olan ve zanaatle var olan ayrımında ikincisine denk düşmüş ve ...
Şeyma Nur Tan
doaj   +1 more source

Developing whole-school assessment [PDF]

, 2009
"Getting assessment systems right in schools is not an easy task. We think there are five main challenges to meet, summarised here [in this document].

core