Results 171 to 180 of about 900,875 (297)

The First Advent of the Whole Genome Sequencing Cohort in Japan. [PDF]

JMA J
Suzuki Y.
europepmc   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Whole genome sequencing data of 14 indigenous Greek goats. [PDF]

Sci Data
Tsoureki A, Michailidou S, Vouraki S, Boukouvala E, Arsenos G, Sakaridis I.   +5 more
europepmc   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

Whole genome sequencing of hepatitis A virus: adapting Illumina protocols for foodborne investigation. [PDF]

NPJ Sci Food
Yeo D, Jung S, Hwang S, Yoon D, Lim DJ, Jin S, Choi J, Hong KH, Choi C.   +8 more
europepmc   +1 more source

Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits [PDF]

, 2017
et al,, Locke, Adam
core   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Whole genome sequencing approach to assess homologous recombination deficiency in a pan-cancer cohort. [PDF]

Commun Med (Lond)
Al Assaad M, Hadi K, Levine MF, Guevara D, Patel M, Tranquille M, King A, Otilano J, Semaan A, Gundem G, Medina-Martínez JS, Sigouros M, Manohar J, Kuo HH, Wilkes DC, Andreopoulou E, Chapman-Davis E, Tagawa ST, Sboner A, Ocean AJ, Shah MA, Papaemmanuil E, Sternberg CN, Holcomb K, Nanus DM, Elemento O, Mosquera JM.   +26 more
europepmc   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

The genomic diversity and spatial patterns of Mycobacterium bovis in Ireland revealed by whole genome sequencing. [PDF]

Ir Vet J
O'Shaughnessy J, Harvey N, Byrne B, McElroy M, Gutierrez M, Murphy D, Kenny K, Cameron H, Prendergast D, Cupial R, Goggin M, Dygico LK, Smith J, Tratalos JA, Devaney R, Ranasinghe P, Ardis T, Allen A, McGrath G, Gordon SV, Farrell D.   +20 more
europepmc   +1 more source