Results 281 to 290 of about 1,170,509 (350)

Leveraging illumina iSeq100 for whole genome sequencing of Salmonella Typhi for a resource-limited setting. [PDF]

Sci Rep
Katuwal N, Naga SR, Shrestha A, Shahi SB, Tamrakar D, Shrestha R.   +5 more
europepmc   +1 more source

Congenital Langerhans Cell Histiocytosis With Novel KCL1::RAF1 Gene Fusion Identified Through Routine Whole‐Genome Sequencing [PDF]

Fred A. Wright, Gemma Barnard, Shivani Bailey, C. Elizabeth Hook, Nicholas Coleman, Natasha Stembridge, Rowena Guermech, James Watkins, Jamie Trotman, Patrick Tarpey, Vasanta Nanduri, Matthew J. Murray   +11 more
openalex   +1 more source

Microfilament‐Myosin II Regulates the Differentiation of Multinucleated Cysts into Oocytes and Influences Oocyte Developmental Potential in Mice

Advanced Science, EarlyView.
In this study, we provided new evidence identifying multinucleated cysts as precursors for oocyte differentiation. Within these cysts, organelles migrate and aggregate to form Balbiani body (B‐body) and establish early cellular polarity. Concurrently, excess nuclei are expelled, enabling cyst‐to‐oocyte differentiation. The microfilament‐myosin II plays
Rui Xu, Menghao Pan, Zhi Zheng, Yaju Tang, Yutong Yan, Sihai Lu, Sha Peng, Baohua Ma   +7 more
wiley   +1 more source

WHOLE GENOME SEQUENCING OF ENTEROBACTER CLOACAE SM32 IN THE FIRST ISOLATION OF THE MEDICAGO SATIVA L. ROOT NODULES IN MOSUL, IRAQ CAPABLE OF PRODUCING INDOLE-3-ACETIC ACID [PDF]

Suleman Mohammed, Raad Hassani Sultan, Vineetha Edavana   +2 more
openalex   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Single cell long read whole genome sequencing reveals somatic transposon activity in human brain. [PDF]

Commun Biol
Izydorczyk MB, Kalef-Ezra E, Horner DW, Zheng X, Holmes N, Toffoli M, Sahin Z, Han Y, Mehta HH, Scholz SW, Dalgard CL, Muzny DM, Ameur A, Sedlazeck FJ, Proukakis C.   +14 more
europepmc   +1 more source

Epidemiological links between tuberculosis cases identified twice as efficiently by whole genome sequencing than conventional molecular typing: A population-based study

, 2018
Rana Jajou, Albert J. de Neeling, Rianne van Hunen, Gèrard de Vries, Henrieke Schimmel, A. Mulder, Richard Anthony, Wim van der Hoek, Dick van Soolingen   +8 more
openalex   +2 more sources

PRDM16 Reduces Cellular Senescence by Upregulating GSTM1

Advanced Science, EarlyView.
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan, Yuting Zhu, Ben Tang, Yaru Xie, Mingcun Hu, Hua Su, Youhua Liu, Chun Zhang   +7 more
wiley   +1 more source

Whole-Genome Sequencing Analysis of Drug-Resistant <i>Salmonella Typhi</i> in Children. [PDF]

Pathogens
Riaz M, Ahmad S, Sattar F, Li G, Din ZU, Ahmad S, Azra, Waheed A, Ul Haq I, Phelan JE, Rani GF, Cabral-Marques O, Campino S, Khan TA, Clark TG.   +14 more
europepmc   +1 more source

Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions

Advanced Science, EarlyView.
Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley   +1 more source