Results 91 to 100 of about 59,931 (229)

Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation [PDF]

, 2015
BACKGROUND: Potential involvement of the CCR10/CCL28 axis was recently reported in murine models of allergic asthma. If confirmed, blockade of the CCR10 receptor would represent an alternative to current asthma therapies.
Eric Chevalier, François Daubeuf, Françoise Jung, Garry J. Douglas, Nelly Frossard   +4 more
core   +1 more source

Free‐Breathing Magnetization Transfer Imaging of the Lung at 0.55 T Using bSTAR

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a clinically applicable method for magnetization transfer (MT) imaging of the lung at 0.55 T. Methods MT imaging of the chest was explored in healthy volunteers at 0.55 T using a self‐gated 3D half‐radial dual‐echo balanced steady‐state free precession sequence (bSTAR), a 2D multi‐slice gradient echo method (GRE) acquired in
Alexandra Braun, Grzegorz Bauman, Maurice Pradella, Jonathan Röcken, Katrin E. Hostettler, Oliver Bieri   +5 more
wiley   +1 more source

Bilateral whole lung lavage in pulmonary alveolar proteinosis – A retrospective study

Revista Portuguesa de Pneumologia, 2014
Whole lung lavage (WLL) is the gold standard technique for the treatment of Pulmonary Alveolar Proteinosis (PAP). In this paper we evaluated and discuss bilateral WLL, namely the procedure work-up and the therapeutic efficacy.Six bilateral WLL performed ...
A. Silva, A. Moreto, C. Pinho, A. Magalhães, A. Morais, C. Fiuza   +5 more
doaj   +1 more source

In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury [PDF]

, 2006
Background: Intravenous salbutamol (albuterol) reduces lung water in patients with the acute respiratory distress syndrome (ARDS). Experimental data show that it also reduces pulmonary neutrophil accumulation or activation and inflammation in ARDS ...
McAuley, Daniel F., Nathani, N., Perkins, Gavin D., Smith, F. Gao (Fang Gao), Thickett, David R.   +4 more
core   +1 more source

Radiographic evaluation of gastroliths in a group of 49 juvenile saltwater crocodiles (Crocodylus porosus) in the UK

Veterinary Record, EarlyView.
Abstract Background Gastrolith ingestion is a known inherent behaviour in crocodiles. However, the interpretation of coelomic radiographs in crocodilians is challenging due to the limited informative literature in this field. Methods Dorsoventral coelomic radiographs of 49 juvenile saltwater crocodiles (Crocodylus porosus) were acquired twice, with an ...
Charlotte R. Nix, Ellie R. John, Iain Cope, Katherine Hughes, Marie‐Aude Genain   +4 more
wiley   +1 more source

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. [PDF]

, 1996
Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain unclear. Human studies have correlated aberrant activation of T helper (Th) 2-like effector systems in the airways with disease. A
Corry, DB, Erle, DJ, Folkesson, HG, Locksley, RM, Matthay, MA, Warnock, ML, Wiener-Kronish, JP   +6 more
core  

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Rituximab for auto-immune alveolar proteinosis, a real life cohort study

Respiratory Research, 2018
Background Whole lung lavage is the current standard therapy for pulmonary alveolar proteinosis (PAP) that is characterized by the alveolar accumulation of surfactant.
Berenice Soyez, Raphael Borie, Cedric Menard, Jacques Cadranel, Leonidas Chavez, Vincent Cottin, Emmanuel Gomez, Sylvain Marchand-Adam, Sylvie Leroy, Jean-Marc Naccache, Hilario Nunes, Martine Reynaud-Gaubert, Laurent Savale, Abdellatif Tazi, Lidwine Wemeau-Stervinou, Marie-Pierre Debray, Bruno Crestani   +16 more
doaj   +1 more source

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer. [PDF]

, 2014
The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures ...
Haisheng eXu, Wenbin eDeng, Wenbin eDeng, Wenrong eGong, Xin eQin   +4 more
core   +2 more sources

Respiratory and Circulatory changes during whole-lung lavage

THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA, 1983
3 patients suffering from alveolar proteinosis were treated with massive pulmonary lavage. The lavage method followed the technique described by Ramirez-R, in which one lung was degassed and irrigated repeatedly by liters of a warmed saline solution. During lung lavage, percutaneous and intra-arterial PO2 electrodes were used to monitor the blood gas ...
Minoru KAWANISHI, Masaji MATSUURA, Junichi HASEGAWA, Motoshi KAINUMA, Yoshimichi NAMBA, Toshiyuki MIYAKE, Noboru TAKESHIMA   +6 more
openaire   +2 more sources