Whole lung lavage - Open Access .click

Results 111 to 120 of about 63,209 (242)

Local lung hypoxia determines epithelial fate decisions during alveolar regeneration. [PDF]

, 2017
After influenza infection, lineage-negative epithelial progenitors (LNEPs) exhibit a binary response to reconstitute epithelial barriers: activating a Notch-dependent ΔNp63/cytokeratin 5 (Krt5) remodelling program or differentiating into alveolar type II
Brumwell, Alexis N +13 more
core +1 more source

Protective Role for Itaconate During Inhaled Allergen Challenge

Allergy, EarlyView.
Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers +16 more
wiley +1 more source

Increased levels of hyaluronic acid in bronchoalveolar lavage from patients with interstitial lung diseases, relationship with lung function and inflammatory cells recruitment [PDF]

, 2014
Purpose: Interstitial Lung Diseases (ILD) are characterized by inflammation and fibrosis. It described the role of hyaluronic acid (HA) as an immune-regulator. It is not known if HA contributes to the recruitment of inflammatory cells associated with ILD.
Auteri, Santiago +6 more
core +1 more source

The benefits of whole lung lavage in pulmonary alveolar proteinosis [PDF]

European Respiratory Journal, 2004
Pulmonary alveolar proteinosis (PAP) is an interesting, rare and enigmatic disease, which was first described relatively recently in 1958 1. The affected individuals suffer a progressive accumulation of lipoproteins in the alveolar space, resulting in steadily worsening gas exchange, and culminating in death from hypoxia and or cor pulmonale.
openaire +2 more sources

Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments

Allergy, EarlyView.
ABSTRACT Background Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated an EAACI‐endorsed update of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines (ARIA 2024 ...
Bernardo Sousa‐Pinto +252 more
wiley +1 more source

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer. [PDF]

, 2014
The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures ...
Haisheng eXu +4 more
core +2 more sources

Therapeutic Effect of Whole Lung Lavage on Pneumoconiosis

EMJ Respiratory, 2016
Pneumoconiosis as an occupational disease is a serious threat to the health of workers. Patients with pneumoconiosis are mainly engaged in dust-related work such as gold, coal, or iron mining, electric welding, or road work, and present with miliary nodules, fuse mass-like opacities, and cavity lesions on chest imaging.
Hongmei Zhang +4 more
openaire +1 more source

Climate Change, Air Quality, and Pollen Allergies—State of the Art and Recommendations for Research and Public Health

Allergy, EarlyView.
ABSTRACT Allergies are one of the major health challenges of our time, associated with a high individual burden of disease and high costs for the healthcare system. Given their prevalence, allergies are also highly relevant from a public health perspective. The development of allergic diseases is multifactorial. In addition to individual factors (e.g.,
Jobst Augustin +13 more
wiley +1 more source

Pulmonary surface-active materials in the Chediak-Higashi syndrome.

Journal of Lipid Research, 1978
Beige mice express the Chediak-Higashi syndrome. Large inclusions, identified as abnormal lysosomes, are found in many cells. The inclusions in type II alveolar epithelial cells are enlarged lamellar bodies and they are associated with an increase in ...
J L Prueitt, E Y Chi, D Lagunoff
doaj +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

British Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam +12 more
wiley +1 more source

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diseases of the respiratory system
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pneumoconiosis