Results 141 to 150 of about 63,209 (242)

Distinct alterations of adiponectin, fibroblast growth factor 21 (FGF‐21), and insulin‐like growth factor binding protein 2 (IGFBP‐2) link dysmetabolism with cognitive decline across the Alzheimer's disease spectrum

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Metabolic disorders are risk factors for Alzheimer's disease (AD), although underlying mechanisms remain unclear. We investigated the relationship between peripheral metabolic markers – adiponectin, fibroblast growth factor 21 (FGF‐21), and insulin‐like growth factor binding protein 2 (IGFBP‐2) – and AD.
Caroline Dallaire‐Théroux   +15 more
wiley   +1 more source

Proteolytic enzyme systems [PDF]

open access: yes, 1993
Fritz, Hans   +4 more
core   +1 more source

Lung Injury Pathways: Adenosine Receptor 2B Signaling Limits Development of Ischemic Bronchiolitis Obliterans Organizing Pneumonia [PDF]

open access: yes, 2017
Purpose/Aim of the Study: Adenosine signaling was studied in bronchiolitis obliterans organizing pneumonia (BOOP) resulting from unilateral lung ischemia. Materials and Methods: Ischemia was achieved by either left main pulmonary artery or complete hilar
Auchampach, John   +9 more
core   +1 more source

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Inhaled Halogen‐Induced Oxidative Renal Damage and Dysfunction: A Lung Heart Kidney Axis

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
Mechanisms of lung‐heart‐kidney interaction in inducing organ injury after chemical inhalation. Acute exposure to halogen gases causes extensive lung injury and acute cardiac damage leading to fatalities. Formation of highly reactive halogenated molecules in the pulmonary bed and their circulation resulting in oxidative stress and inflammation was ...
Juan Xavier Masjoan Juncos   +9 more
wiley   +1 more source

High‐throughput single‐cell DNA methylation and chromatin accessibility co‐profiling with SpliCOOL‐seq

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
SpliCOOL‐seq achieves high‐throughput single‐cell co‐profiling of DNA methylation and chromatin accessibility. DNMT inhibitors caused cancer cell demethylation with divergent patterns. SpliCOOL‐seq enables the discovery of genes related to LUAD tumorigenesis. Ageing and LUAD tumorigenesis may share similar epigenetic alterations.
Qingmei Shen   +6 more
wiley   +1 more source

Management of a case of oil drowning with whole lung lavage - Challenges and solutions. [PDF]

open access: yesIndian J Anaesth, 2021
Thondebhavi SM   +3 more
europepmc   +1 more source

Investigating the Role of A20 in Respiratory Syncytial Virus Immunopathogenesis in a BALB/c Mouse Model

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Respiratory syncytial virus (RSV) is a leading cause of acute respiratory tract infections in children and the elderly worldwide. RSV pathogenesis is largely driven by exaggerated host immune responses that result in lung injury.
Alireza Tahamtan   +5 more
wiley   +1 more source

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