Rituximab Therapy in Pulmonary Alveolar Proteinosis: A Rare Case Report [PDF]
Pulmonary Alveolar Proteinosis (PAP) is a rare disorder characterised by accumulation of surfactant in alveoli due to impaired surfactant clearance. Although, whole lung lavage is the standard treatment of PAP, rituximab has also been introduced as a ...
Fatemeh Aghaei Meybodi +3 more
doaj +1 more source
Venoarterial extracorporeal membrane oxygenation (ECMO) for support during whole lung lavage for pulmonary alveolar proteinosis. [PDF]
INTRODUCTION ECMO as support during whole lung lavage (WLL) for pulmonary alveolar proteinosis is reserved for severe cases where oxygenation is inadequate to support the patient using the ventilator alone.
Cavarocchi, Nicholas C +4 more
core +2 more sources
Whole lung lavage combined with Granulocyte-macrophage colony stimulating factor inhalation for an adult case of refractory pulmonary alveolar proteinosis [PDF]
BACKGROUND: Whole-lung lavage (WLL) is classically the first-line treatment for symptomatic pulmonary alveolar proteinosis (PAP). However, some patients require multiple WLLs because of refractory nature of their PAP. In this instance, these patients may
Hong yan Yu +4 more
core +2 more sources
Pulmonary alveolar proteinosis treatment by whole-lung lavage [PDF]
Pulmonary alveolar proteinosis (PAP) is a rare condition which is characterised by the abnormal accumulation of proteinaceous material in the alveolar spaces, with resulting impairment in oxygen exchange across the involved alveoli. The diagnosis of PAP can be established by the classic ‘milky’ effluent bronchoalveolar lavage fluid (BALF).
Cai, Chang +3 more
openaire +2 more sources
Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats [PDF]
The increasing use of silver nanoparticles (AgNPs) in consumer products is concerning. We examined the potential toxic effects when inhaled in Brown-Norway (BN) rats with a pre-inflammatory state compared to Sprague-Dawley (SD) rats.We determined the ...
Buckley, A +17 more
core +1 more source
Pulmonary alveolar proteinosis after lung transplantation
We report the case of a 69‐year‐old man five‐month post double lung transplant for idiopathic pulmonary fibrosis (IPF) who presented with progressive breathlessness, loss of lung function, and diffuse ground glass shadowing on the chest computed ...
Chandima Divithotawela +4 more
doaj +1 more source
Whole lung lavage in pulmonary alveolar proteinosis: anesthetic management and challenges
Background Pulmonary alveolar proteinosis is a rare disorder characterized by alveolar obstruction secondary to the collection of lipoproteinaceous material in the alveoli leading to a spectrum of respiratory illness ranging from mild to severe ...
Manisha Manohar, Priyanka Bansal
doaj +1 more source
Apoptosis in the lungs of pigs infected with porcine reproductive and respiratory syndrome virus and associations with the production of apoptogenic cytokines [PDF]
International audienceApoptosis was studied in the lungs of pigs during an infection with a European strain of porcine reproductive and respiratory syndrome virus (PRRSV) and it was examined if cytokines were involved in the induction of apoptosis ...
Labarque, Geoffrey +4 more
core +3 more sources
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Alveolar Proteinosis in COVID-19: Clinical Case
Pulmonary alveolar proteinosis (PAP) is a rare, diffuse lung disease characterized by accumulation of lipoprotein in lung surfactant in the alveolar space and terminal bronchioles, leading to impaired gas exchange and arterial hypoxemia.
Silvia Martin Bote +4 more
doaj +1 more source

