Results 71 to 80 of about 63,209 (242)
Advanced Science, EarlyView.This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang +14 more
wiley +1 more source
Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]
, 2016 Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and ...
Adcock, IM +5 more
core +4 more sources
Lung Ultrasound Scans During Whole Lung Lavage [PDF]
Chest, 2021 Matthew J G, Sigakis +1 more
openaire +2 more sources
Advanced Science, EarlyView.Tumor‐derived extracellular vesicles program inflammatory lung premetastatic niches through selective delivery of long noncoding RNAs. This work reveals EVs‐associated lncOSLMT as a key driver of lung fibroblast activation via m6A‐dependent PTGS2 stabilization.
Hongbo Li +10 more
wiley +1 more source
Inhaled Interleukin-10 before and after induction of experimental endotoxemia in the rat : effects on the inflammatory response [PDF]
, 2007 To determine the effects of inhaled IL-10 at different doses and different time points on the pulmonary and systemic inflammatory response during endotoxemia, 48 ventilated, anaesthetized rats (mean body weight ± standard deviation, 500 ± 33g) were ...
Nguyen, Ngoc-Thach
core
Ovalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotype [PDF]
, 2010 Background Recent studies have indicated the presence of multipotent mesenchymal stromal cells (MSCs) in human lung diseases. Excess airway smooth muscle, myofibroblasts and activated fibroblasts have each been noted in asthma, suggesting that ...
Adam M Goldsmith +8 more
core +6 more sources
Transoesophageal echocardiography in the management of whole lung lavage
British Journal of Anaesthesia, 1998 The effects of two lung ventilation, one lung ventilation and alveolar lavage on right ventricular mechanics in a patient have been observed using transoesophageal echocardiography (TOE). Alveolar lavage resulted in additional stresses to those of one lung ventilation (OLV) and the point when these were noted to be resulting in right ventricular ...
C C, Mcmahon, T, Irvine, I D, Conacher
openaire +2 more sources
Advanced Science, EarlyView.We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng +13 more
wiley +1 more source
Respiratory Medicine Case Reports, 2019 Introduction: Pulmonary alveolar proteinosis is a rare disease that is characterized by accumulation of surfactant and phospholipids in the pulmonary alveoli. The current mainstay of treatment is whole lung lavage.
Haiyan Zhang
doaj +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Advanced Science, EarlyView.Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source