Results 81 to 90 of about 59,931 (229)

Surmounting Recalcitrant Airway Inflammatory Disorders With a Multi‐Targeting Therapeutic Strategy by Tannic Acid‐Modified CuInP2S6 Nanosheets

Exploration, EarlyView.
Our findings underscore a multi‐targeting strategy for severe airway inflammation that multi‐targeting nanoformulation C‐TA1 markedly attenuated airway inflammation by (1) cfDNA elimination to alleviate neutrophilic/eosinophilic inflammation mediated by the TLR9 pathway, (2) prevention of RONS‐induced tissue injury and inflammatory response, (3 ...
Ming Liu, Changyi Xu, Renqiang Ma, Xinran Xie, Ying Xie, Mengya Du, Zhaofeng Xu, Shuaiyin Zhang, Jian Li, Weiping Wen, Zhaoxu Tu   +10 more
wiley   +1 more source

気管支喘息の臨床分類とその細胞性および液性因子の特徴 [PDF]

, 1993
Characteristics of each asthma type classified by clinical symptoms and　findings were studied in 72 patients with bronchial asthma. 1. Ventilatory function tests showed that the values of % MMF, % V(50) and % V(25) were significantly lower in patients ...
Hiramatsu, Junichi, Kajimoto, Kazuhiro, Kawaraya, Masashi, Kimura, Ikuro, Kitani, Hikaru, Mifune, Takashi, Mitsunobu, Fumihiro, Nakagiri, Yoshiyasu, Sugimoto, Keisuke, Tada, Shinya, Tanizaki, Yoshiro, Yokota, Satoshi   +11 more
core   +1 more source

Visible Photosensitizing Disinfectant Spray for Combating Multidrug‐Resistant Candidozyma Auris in Healthcare Settings

Exploration, EarlyView.
We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu, Ming‐Yu Wu, Baoping Li, Jie Li, Siyu Chen, Luojia Chen, Donghu Yu, Liupiaopiao Yang, Ziyu Hong, Huaqin Pan, Wei Xiang, Shun Feng, Jong Seung Kim, Lianrong Wang, Zhiqiang Li, Shi Chen, Meijia Gu   +16 more
wiley   +1 more source

Nutritional, phytochemical, and potential health benefits of Monostroma spp.: A systematic review

Food Biomacromolecules, EarlyView.
Abstract Monostroma spp., belonging to the green seaweed, has been known to be health‐promoting food items as prophylactic agents worldwide. It has shown wide arrays of bioactivities for the prevention and treatment of various diseases. A total of 47 articles were selected to review following the Preferred Reporting Items for Systematic reviews and ...
Md Shariful Islam
wiley   +1 more source

Effect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant response [PDF]

, 2014
Exposure of lung to hypoxia has been previously reported to be associated with significant alterations in the protein content of bronchoalveolar lavage (BAL) and lung tissue.
Floros, Joanna, López Barneo, José, Olmeda, Bárbara, Pascual Bravo, Alberto, Phelps, David S., Pérez Gil, Jesús, Silveyra, Patricia, Umstead, Todd M.   +7 more
core   +1 more source

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini, Francesca Caloni, Paola Fossati, Giancarlo Ruffo, Luciana Rossi   +4 more
wiley   +1 more source

Low‐value care and variation in practice in the care of children hospitalized with bronchiolitis in Canada (CareBEST): Protocol for a multi‐center prospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Introduction Low‐value care refers to health services for which the potential harms or costs outweigh the benefits of use. Bronchiolitis is the most common and among the most costly causes of pediatric hospitalizations. Evidence consistently shows that many common tests and treatments used to manage bronchiolitis do not improve outcomes ...
Branden Bonham, Tamara Perez, Michelle Bailey, Nick Barrowman, Christopher Bonafide, Ariane Boutin, Melanie Buba, Francine Buchanan, Matthew Carwana, Breanna A. Chen, Evelyn Constantin, Kim de Castris Garcia, Francesca del Giorgio, Zachary Dionisopoulos, Christine Fahim, Karen L. Forbes, Jeremy N. Friedman, Josée Anne Gagnon, Peter J. Gill, Mei Han, Nelly Huynh, Maria Karaceper, Terry P. Klassen, Isabelle Lahaie, Patricia Li, Myla Moretti, Sanjay Mahant, Sarah Manos, Hayat Mekhici, Chris Novak, Olivia Ostrow, Caroline Quach, Julie Quet, Mahmoud Sakran, Anupam Seghal, Alan R. Shroeder, Marc‐André Turcot, Gita Wahi, Olivier Drouin, The Canadian Pediatric Inpatient Research Network (PIRN)   +39 more
wiley   +1 more source

Bronchoscopic lung cryobiopsy for the diagnosis of pulmonary alveolar proteinosis in a hypoxemic patient

Lung India, 2020
Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by the intra-alveolar accumulation of surfactant due to macrophage dysfunction or the production of abnormal surfactant.
Vikas Marwah, C D S Katoch, P Sengupta, Saikat Bhattacharjee   +3 more
doaj   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Clearance In Vivo of Instilled [H]Cholesterol from the Rat Lung

Biochemistry Research International, 2010
Phospholipids and lung surfactant proteins are known to be recycled within the lung alveolus mainly by uptake into type II epithelial cells that secrete lipid-enriched lung surfactant. Dipalmitoyl phosphatidylcholine (DPPC) is the major component of lung
Michael A. Wyder, Shannon M. Griffin, D. Nicole Worsham, Edna S. Kaneshiro   +3 more
doaj   +1 more source