Tiled top-down pyramids and segmentation of large histological images
International audienceRecent microscopic imaging systems such as whole slide scanners provide very large (up to 18GB) high resolution images. Such amounts of memory raise major issues that prevent usual image representation models from being used ...
Brun, Luc +2 more
core +1 more source
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon +10 more
wiley +1 more source
An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio +8 more
wiley +1 more source
HMHGT: Hierarchical Multi-Scale Hypergraph Representation for Histopathology Whole Slide Images
Cancer prognosis is a challenging task in computational pathology, requiring comprehensive representation of tissue features with context awareness to more accurately infer patient survival. However, existing deep learning methods, such as multi-instance
Shangce Wang, Lukai Jiang, Chenggong Qiu
doaj +1 more source
Unsupervised Domain Adaptation for Classification of Histopathology Whole-Slide Images
Computational image analysis is one means for evaluating digitized histopathology specimens that can increase the reproducibility and reliability with which cancer diagnoses are rendered while simultaneously providing insight as to the underlying ...
Jian Ren +5 more
doaj +1 more source
Color standardization and optimization in Whole Slide Imaging [PDF]
Standardization and validation of the color displayed by digital slides is an important aspect of digital pathology implementation. While the most common reason for color variation is the variance in the protocols and practices in the histology lab, the color displayed can also be affected by variation in capture parameters (for example, illumination ...
openaire +3 more sources
Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
Scale Stain: Multi-Resolution Feature Enhancement in Pathology Visualization
Digital whole-slide images of pathological tissue samples have recently become feasible for use within routine diagnostic practice. These gigapixel sized images enable pathologists to perform reviews using computer workstations instead of microscopes ...
Bodén, Anna +4 more
core
Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar +4 more
wiley +1 more source
H&E-stained Whole Slide Image Deep Learning Predicts SPOP Mutation State in Prostate Cancer [PDF]
Andrew J. Schaumberg +2 more
openalex +1 more source

