Results 71 to 80 of about 345,506 (334)

Development and use of a genitourinary pathology digital teaching set for trainee education

Journal of Pathology Informatics, 2010
Background : Automated, high-speed, high-resolution whole slide imaging (WSI) robots are becoming increasingly robust and capable. This technology has started to have a significant impact on pathology practice in various aspects including resident ...
Li Li, Bryan J Dangott, Anil V Parwani
doaj   +1 more source

Classification of Thyroid Carcinoma in Whole Slide Images Using Cascaded CNN

IEEE Access, 2021
The objective of this research is to build a “Whole Slide Images” classification system using Convolutional Neural Network (CNN). This system is capable of classifying Thyroid tumors into three types: Follicular adenoma, follicular ...
Ahmed S. El-Hossiny, Walid Al-Atabany, Osama Hassan, Ahmed M. Soliman, Sherif A. Sami   +4 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Utilizing a Pathomics Biomarker to Predict the Effectiveness of Bevacizumab in Ovarian Cancer Treatment

Bioengineering
The purpose of this investigation is to develop and initially assess a quantitative image analysis scheme that utilizes histopathological images to predict the treatment effectiveness of bevacizumab therapy in ovarian cancer patients.
Patrik Gilley, Ke Zhang, Neman Abdoli, Youkabed Sadri, Laura Adhikari, Kar-Ming Fung, Yuchen Qiu   +6 more
doaj   +1 more source

Mutual Contrastive Low-rank Learning to Disentangle Whole Slide Image Representations for Glioma Grading [PDF]

, 2022
Lipei Zhang, Yiran Wei, Ying Fu, S. D. Price, Carola‐Bibiane Schönlieb, Chao Li   +5 more
openalex   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

PATMA: parser of archival tissue microarray [PDF]

PeerJ, 2016
Tissue microarrays are commonly used in modern pathology for cancer tissue evaluation, as it is a very potent technique. Tissue microarray slides are often scanned to perform computer-aided histopathological analysis of the tissue cores.
Lukasz Roszkowiak, Carlos Lopez
doaj   +2 more sources

Evaluation of Joint Multi-Instance Multi-Label Learning For Breast Cancer Diagnosis [PDF]

, 2015
Multi-instance multi-label (MIML) learning is a challenging problem in many aspects. Such learning approaches might be useful for many medical diagnosis applications including breast cancer detection and classification.
Aksoy, Selim, Gecer, Baris, Tasar, Onur, Yalcinkaya, Ozge   +3 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Classifying Whole Slide Images: What Matters?

, 2023
Recently there have been many algorithms proposed for the classification of very high resolution whole slide images (WSIs). These new algorithms are mostly focused on finding novel ways to combine the information from small local patches extracted from the slide, with an emphasis on effectively aggregating more global information for the final ...
Nguyen, Long, Nibali, Aiden, Millward, Joshua, He, Zhen   +3 more
openaire   +2 more sources