Results 31 to 40 of about 140,750 (200)

The WID-CIN test identifies women with, and at risk of, cervical intraepithelial neoplasia grade 3 and invasive cervical cancer

open access: yesGenome Medicine, 2022
Background Cervical screening is transitioning from primary cytology to primary human papillomavirus (HPV) testing. HPV testing is highly sensitive but there is currently no high-specificity triage method for colposcopy referral to detect cervical ...
James E. Barrett   +7 more
doaj   +1 more source

Review: A Sadly Trouble History: The Meanings of Suicide in the Modern Age [PDF]

open access: yes, 2010
The article reviews the book “A Sadly Trouble History: The Meanings of Suicide in the Modern Age”, By John ...
Coleborne, Catharine
core   +1 more source

Proteinvermittelte Kupfer‐Redoxregulation: Rolle von Disulfidbrücken und allosterischer Modulation

open access: yesAngewandte Chemie, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann   +9 more
wiley   +1 more source

The Balancing Act: Creating New Academic Support in Writing While Honoring The Old [PDF]

open access: yes, 2013
In 2009, our university launched a Writing Across the Curriculum (WAC) Program in response to an accreditation core requirement to focus a universitywide initiative on student learning, often referred to as the Quality Enhancement Plan.
Barganier, Susan, Good, Jennifer
core   +1 more source

Liganden der Lipidtasche induzieren allosterische Modulation der Proteindynamik im Bereich des aktiven Zentrums der Proteinkinase p38α

open access: yesAngewandte Chemie, EarlyView.
Bei der Suche nach neuen allosterischen Stellen in der Serin/Threonin‐Kinase p38α deckt die NMR‐Spektroskopie eine dynamische Kopplung zwischen dem katalytischen Zentrum und der Lipidtasche auf. Die Ergebnisse offenbaren bewegungsbezogene Interdependenzen, die entfernte Regionen des Enzyms miteinander verbinden, was die Lipidtasche als ...
Sara Medina Gómez   +4 more
wiley   +1 more source

The variability of wave-in-deck loading in random seas: a data-driven approach

open access: yesApplied Ocean Research
This study investigates wave-in-deck (wid) loading in random sea-states. These are among the most severe forces experienced by offshore structures and a critical factor in assessing their reliability.
Chong Huo, Li Ma, Ioannis Karmpadakis
doaj   +1 more source

Brecht - Galileo [PDF]

open access: yes, 2010
This is the age of doubt, says Brecht's Galileo, the 17th century scientist. "It ain't necessarily so," says Gershwin's Sportin' Life of the 1930ies. "De t'ings dat yo li'ble / to read in de Bible / it ain't necessarily so.
Deinert, Herbert
core  

Iterated weak dominance and interval-dominance supermodular games [PDF]

open access: yes, 2019
This paper extends Milgrom and Robert's treatment of supermodular games in two ways. It points out that their main characterization result holds under a weaker assumption.
Sobel, Joel
core   +1 more source

Der Nicht‐Adiabatische Charakter von Substituenteneffekten in Azobenzol

open access: yesAngewandte Chemie, EarlyView.
Vereinheitlichung Nicht‐Adiabatischen Schaltens: die thermische Z→E Isomerisierung von para‐substitutierten Azobenzolen verläuft über einen einzelnen Reaktionsweg mit nicht‐adiabatischem Charakter. Anstatt eines mechanistischen Wechsels spiegelt der bekannte V‐förmige Hammett Graph ein Artefakt des σp Parameters, zeigt so die Grenzen von DFT auf und ...
Jacob Jan van der Wal   +4 more
wiley   +1 more source

Contradictions regarding teaching and writing (or writing to learn) in the disciplines: What we have learned in the USA

open access: yesRed U, 2013
This article describes a tradition of Anglophone North American higher education (HE) research concerning the role of writing in learning and development. The research tradition is associated with a forty-year-old education reform movement called Writing
David R. Russell
doaj   +1 more source

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