Results 131 to 140 of about 16,814,361 (358)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

The impact of population-wide rapid antigen testing on SARS-CoV-2 prevalence in Slovakia [PDF]

, 2020
Martin Pavelka, Kevin van Zandvoort, Sam Abbott, Katharine Sherratt, Marek Majdán, Inštitút Zdravotných Analýz, Pavol Jarčuška, Marek Krajčí, Stefan Flasche, Sebastian Funk, Sebastian Funk   +10 more
openalex   +1 more source

Nonsteroidal anti-inflammatory drug hypersensitivity syndrome. A multicenter study I. clinical findings and in vitro diagnosis [PDF]

, 2009
ackground: We present the results obtained from the largest series of in vitro diagnostic tests ever reported in patients with clinically validated hypersensitivity to acetylsalicylic acid (ASA)/nonsteroidal anti-infl ammatory drugs (NSAID) compared ...
Aberer, W. (W.), Blanca, M. (M.), Correia, S. (S.), Erdman, S. (S.), Gamboa, P.M. (P. M.), Jermann, J.S. (J. S.), Kanny, G. (G.), Kowalski, M. (M.), Mayorga, L. (L.), Medrala, W. (W.), Merk, A. (A.), Sainte-Laudy, J. (J.), Sanz, M.L. (María Luisa), Schneider, M.S. (M.S.), Sczczeklik, A. (A.), Sturm, G.J. (G.J.), Weber, J.M. (J.M.), Weck, A.L. (A.L.) de, Wedi, A. (A.)   +18 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Estimation of Typhoid Fever Between Healthy Students of Wasit University

Wasit Journal for Pure Sciences
Typhoid fever is endemic in Iraq early diagnosis is necessary to identify the carriers who are responsible for the spread of typhoid fever. our aims to trying to estimate of Salmonella typhi and Salmonella paratyphi antibodies and diagnosis of acute and
Huda Raheem
doaj   +1 more source

The diagnostic value of the widal test in the inoculated [PDF]

Journal of Hygiene, 1948
1. Evidence is given that in recently inoculated persons the Widal reaction, even when serial quantitative tests are done, has no practical value in the diagnosis of enteric fever. Conscription enlarges permanently the inoculated proportion of the whole population.2.
openaire   +2 more sources

Testing Gravity Using Type Ia Supernovae Discovered by Next-Generation Wide-Field Imaging Surveys [PDF]

, 2019
G. Aldering, P. Antilogus, A Bhamanyar, S. BenZvi, H. Courtois, T. M. Davis, Hume A. Feldman, S. Ferraro, Satya Gontcho A Gontcho, A. Gontcho, Or Graur, Romain Graziani, J. Guy, Charlie Harper, Renée Hložek, Cullan Howlett, Dragan Huterer, Chen Ju, P.-F. Léget, E. Linder, P. McDonald, J. Nordin, P. Nugent, S. Perlmutter, N. Regnault, M. Rigault, Shafieloo, A., Slosar, A., Tully, R. B., Wang, L., White, M., Wood-Vasey, M.   +31 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Identification of salmonella typhi by serological and molecular tests isolated from blood

Diyala Journal of Medicine, 2018
Background:Salmonella Typhoid Diagnosis by Widal Test and Polymerase Chain Reaction (PCR). Objective:To study the Isolation and diagnosis of Salmonella typhi,diagnosis of the use of the widal test , diagnosis of Salmonella typhi) using PCR technique ...
Abbas Abod Farhan, Mohammed Shamkhi Jebur, Ruqia Ayad Abbas   +2 more
doaj   +2 more sources

Assessment of sensitivity, specificity and predictive value of Widal test in Typhoid fever patients in Hamadan

مجله دانشگاه علوم پزشکی گرگان, 1999
Serological Widal test is a fast, reliable and easy to perform and this test still is a suitable diagnostic method for diagnosing of typhoidal disease in many clinical laboratories.
Yousefi Mashouf R (PhD), Heidar Barghi Z (BSc)   +1 more
doaj