Results 221 to 230 of about 6,598,574 (279)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Regulatory reform and adult methylphenidate dispensing in France: a nationwide interrupted time-series study. [PDF]

BMJ Ment Health
Saint-Dizier C, Therribout N, Carton L, Icick R, Mercier P, Caron C, Bubrovszky M, Hamroun A, Génin M, Lamer A.   +9 more
europepmc   +1 more source

WIDAL TEST AND ITS MEDICAL SIGNIFICANCE IN DIAGNOSIS

International Journal of Biology, Pharmacy and Allied Sciences, 2019
openaire   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Adult-Onset Still's Disease With Suspected Steroid Hypersensitivity: A Case Report. [PDF]

Cureus
Abdul Gafoor A, Khalid A, Karim T.
europepmc   +1 more source

"Raccoon Eyes": A Rare Presentation of Paediatric Scrub Typhus. [PDF]

J Paediatr Child Health
Raj R, Patra PK, Kumari S.
europepmc   +1 more source

Dengue virus infection amongst malaria and typhoid fever suspected acute febrile patients in the Niger river basin of Nigeria. [PDF]

Sci Rep
Okpanachi RO, Omatola CA, Abraham JO, Okolo MO, Conco-Biyela T, Onoja AB, Adamu AM.   +6 more
europepmc   +1 more source

Disparities in Access to Severe Incontinence Surgical Treatment with Artificial Urinary Sphincter after Radical Prostatectomy in France: A Nationwide Nested Case-control Study. [PDF]

Eur Urol Open Sci
Lenfant L, Taillé Y, Chartier-Kastler E, Lukacs B, Seisen T, Rouprêt M, Beaugerie A, Vicaut E, Mozer PC.   +8 more
europepmc   +1 more source