Results 61 to 70 of about 2,734 (235)

A Neutrophil Membrane‐Encapsulated Pd/hCeO2 Nanoformulation for Alleviating Age‐Dependent Perioperative Neurocognitive Disorders

open access: yesAdvanced Science, EarlyView.
This study reports a neutrophil membrane‐encapsulated Pd/hCeO2 nanozyme (PCN) for targeted treatment of perioperative neurocognitive disorders (PND) in aged mice. PCN inhibits glycolysis‐driven microglial activation and neuroinflammation, improves mitochondrial respiration, and maintains blood‐brain barrier integrity and synaptic function, ultimately ...
Lili Huang   +17 more
wiley   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

open access: yesAdvanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo   +15 more
wiley   +1 more source

C. Bobińska, Wieś niespokojna. Studia małopolskie z XVIII-XIX wieku

open access: yesCzasopismo Prawno-Historyczne, 1980
Recenzja: Celina Bobińska, Wieś niespokojna. Studia małopolskie z XVIII-XIX wieku, Warszawa 1979, Książka i Wiedza, ss. 248.
Kazimierz Orzechowski
doaj   +1 more source

Wieś w programach polskich partii politycznych w okresie 1989-2011

open access: yes, 2011
Artykuł prezentuje wieś w programach partii politycznych w wyborach parlamentarnych w Polsce począwszy od 1989 roku. Są w nim prezentowane programy wyborcze partii, które weszły do Sejmu.
Małgorzata Szpyt
core   +1 more source

The settlement of the Lusatian Urnfield culture discovered at Stara Wieś 24 site, Nadarzyn commune, Mazowieckie Voivodeship [PDF]

open access: yes, 2020
The article presents the results of archaeological excavations carried out in 2016 in connection with the construction of the S8 expressway, at Stara Wieś 24 site.
Ignaczak, Marcin, Affelski, Jakub
core  

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

open access: yesAdvanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu   +12 more
wiley   +1 more source

Pollen analysis of intermoraine deposits from the Sucha Wieś section (Ełk Lakeland, northeastern Poland) [PDF]

open access: yes, 2009
Wyniki analizy pyłkowej międzymorenowej serii dolnego plejstocenu w profilu Sucha Wieś przedstawione są na diagramie pyłkowym, który dokumentuje sukcesję pyłkową z dwoma ciepłymi okresami rangi interglacjału i przedzielającym je okresem chłodnym.
Janczyk-Kopikowa, Z.
core  

Noninvasive Detection and Subtyping of Esophageal Cancer by Circulating Cell‐Free mtDNA Fragmentomics: A Multi‐Center Validation Study

open access: yesAdvanced Science, EarlyView.
Circulating cell‐free mitochondrial DNA provides a robust, noninvasive platform for early detection and histological subtyping of esophageal cancer. This large multi‐center study validates consistently high accuracy across ethnically and geographically diverse cohorts, demonstrating strong potential to transform clinical management. ABSTRACT Esophageal
Yue Liu   +15 more
wiley   +1 more source

Portopulmonary hypertension practice patterns after liver transplantation

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy