Results 241 to 250 of about 1,824,485 (310)

Diversity of astroviruses in wild animals in Yunnan province, China. [PDF]

Virol J
Huang X, Hou J, Le X, Hou Y, Yang L, Li Q, Wang B, Xia X.   +7 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Safety and Immunogenicity of <i>Morbillivirus canis</i> Vaccines for Domestic and Wild Animals: A Scoping Review. [PDF]

Viruses
Rendon-Marin S, Higuita-Gutiérrez LF, Ruiz-Saenz J.   +2 more
europepmc   +1 more source

Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis

Advanced Science, EarlyView.
Inhaled antisense oligonucleotides targeting ANGPTL4 attenuate inflammation, preserve barrier integrity, and reduce fibrosis in both infectious and sterile lung injury models. Integrated transcriptomic analysis reveals a conserved ANGPTL4‐regulated gene network coordinating hypoxic, inflammatory, apoptotic, and stress‐response pathways.
Haiyang Fan, Yuanyang Tan, Junhang Zhang, Xiaoya Liu, Jing Qu, Damien Chua, Hong Sheng Cheng, Joseph Han Sol Kim, Yu Xuan Liu, Changfei Qin, Yingzi Liu, Dezhi Li, Jikang Qiu, Mengshi Chi, Mingmin Bi, Qiwei Zhang, Yun Li, Masoumeh Motamedi Joibari, Stefan K Nilsson, Nguan Soon Tan, Yunping Fan, Liang Li   +21 more
wiley   +1 more source

The Determination of the Prohibited Herbicide 4,6-Dinitro-Ortho-Cresol (DNOC) in Poisoned Domestic and Wild Animals in Italy. [PDF]

Animals (Basel)
Rocchi R, Tinelli A, Gatti G, Badagliacca P, Cocco A, Cantelmi MC, Damiano A, Scortichini G, Merola C, Petrini A.   +9 more
europepmc   +1 more source

CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis

Advanced Science, EarlyView.
Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou, Wan Fu, Shizuo Liu, Zili Zhang, Hanyan Luo, Qing Zhong   +5 more
wiley   +1 more source

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

Metabarcoding of pathogenic parasites based on copro-DNA analysis of wild animals in South Korea. [PDF]

Heliyon
Choi JH, Kim SL, Yoo DK, Yi MH, Oh S, Kim M, Yun S, Yong TS, Choe S, Lee JK, Kim JY.   +10 more
europepmc   +1 more source

Wild animal ways /

, 1916
openaire   +2 more sources

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source