Results 31 to 40 of about 1,063,729 (217)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Solid type primary intraosseous squamous cell carcinoma in a cat
BMC Veterinary Research, 2018 Background Squamous cell carcinoma (SCC) is the most common nonodontogenic oral tumor in cats. In the jaw, it usually presents as an ulceroproliferative lesion associated with enlargement of the affected bone.
Darja Pavlin +3 more
doaj +1 more source
BMC Veterinary Research, 2022 Background Semen cryopreservation has become an essential tool for conservation efforts of the giant panda (Ailuropoda melanoleuca); however, it is severely detrimental to sperm quality.
Ruixue Zhang +11 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Case report: Neuroendocrine carcinoma of the nasal cavity in a roe deer (Capreolus capreolus)
Frontiers in Veterinary ScienceNeuroendocrine tumors of the nasal cavity are rare in both animals and humans. This report describes the macroscopic, histopathological and immunohistochemical characteristics of a neuroendocrine tumor in a three-year-old female roe deer (Capreolus ...
Gorazd Vengušt +5 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Veterinární Medicína, 2017 This report describes recurrent feline gastrointestinal eosinophilic sclerosing fibroplasia (FGESF) and eosinophilic cystitis in an 8-year-old domestic short-haired cat. The cat presented with incontinence, pollakiuria, vomiting and weight loss.
M. Brloznik +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Industrial Crops and ProductsTo address the issues of microecological imbalance and plant growth inhibition caused by continuous cropping soil of Panax ginseng, this study utilized different ratios of pig manure, cow manure, chicken manure, edible fungal medium, and corn stover to ...
Siwei Qiao +7 more
doaj +1 more source