Results 121 to 130 of about 325,483 (256)

Molecular detection of Anaplasma species in blood and ticks from wild ruminants in East Azerbaijan Province, Iran. [PDF]

BMC Vet Res
Esmaeilnejad B, Enferadi A, Mardomi H, Sarani S.   +3 more
europepmc   +1 more source

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

The Ion channel, CFTR, assembles with HIPPO pathway proteins TAZ and YAP in polycystic kidney disease. [PDF]

J Biol Chem
Sharma A, Afshani M, Ciobanu C, Sharma T, Kress JT, Guggino WB, Cebotaru L.   +6 more
europepmc   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

Advanced Science, EarlyView.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li, Chun‐Hui Zhang, Yong Wang, Cheng‐Yuan Li, Da‐Rong Wen, Xi Xia, Liang Zhou, Wei‐Ping Qian, Qing‐Yuan Sun, Chang‐Zhong Li   +9 more
wiley   +1 more source

Landscape Genetics Reveals Geographic Structuring of Locally Adapted Goat Populations from Brazil, Spain, and Ecuador. [PDF]

Genes (Basel)
Castillo Cevallos LA, Rocha LLD, Aguirre Riofrio EL, Martinez Martinez A, Delgado Bermejo JV, Ribeiro MN.   +5 more
europepmc   +1 more source

Pericentrosomal Redistribution of the Endoplasmic Reticulum Ensures Organelle Symmetric Inheritance and Mitotic Progression

Advanced Science, EarlyView.
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu, Yalin Liu, Rongyi Wang, Wenwen Xu, Hao Shi, Ning Huang, Junlin Teng, Jin Meng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

III.—On the Wild Goat and Wild Sheep of the Himalaya, with Remarks on the Genera Capra and Ovis

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +1 more source

Assessment of Anthelmintic Resistance in Major Gastrointestinal Nematodes in Sheep and Goat Farms in Mymensingh, Bangladesh. [PDF]

J Parasitol Res
Islam MR, Mizan MMH, Anisuzzaman, Khatun MS, Ashad FA, Alam MZ, Roy BC, Dey AR.   +7 more
europepmc   +1 more source

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

Strain-dependent differences in the capacity of peste des petits ruminants virus to infect antigen-presenting cells. [PDF]

J Virol
Bouziane A, Lasserre V, Eloiflin R-J, Chambon M, Piro-Mégy C, Guendouz S, Holzmuller P, Totté P, Bataille A.   +8 more
europepmc   +1 more source