Results 61 to 70 of about 2,262,131 (334)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Chinese Journal of Traumatology, 2020 Purpose: The majority of acute anterior shoulder dislocations are sustained during sports and wilderness activities. The management of acute dislocations in the pre-hospital setting is currently without guidelines based on the evidence. The study aims to
Joseph T. Fennelly +5 more
doaj +1 more source
"Bushmeat" and the Origin of HIV/AIDS: A Case Study of Biodiversity, Population Pressures, and Human Health [PDF]
, 2002 The Center for Health and the Global Environment at Harvard Medical School, Population Action International, the Jane Goodall Institute, and the Environmental and Energy Study Institute co-hosted a Congressional briefing, entitled "Bushmeat and the ...
Susan Ziff
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Ibuprofen Blunts Ventilatory Acclimatization to Sustained Hypoxia in Humans. [PDF]
, 2016 Ventilatory acclimatization to hypoxia is a time-dependent increase in ventilation and the hypoxic ventilatory response (HVR) that involves neural plasticity in both carotid body chemoreceptors and brainstem respiratory centers.
Antonova, Julie +7 more
core +6 more sources
Galicia Clínica, 2012 Lesiones debido a un rayo Mujer de 72 años, fue admitida en urgências con dolor abdominal y lipotimia después de ser golpeada por un rayo mientras abría una ventana.
Soraia Oliveira, Andriy Bal
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Two cases of paradoxical hypothermia in a Sahara desert multi-stage ultramarathon
Emergency Care Journal, 2014 Exertional hypothermia in a hot environment, a seemingly contradictory state, is a clinical presentation that has not been previously described in the medical literature.
Elizabeth A. Kaufman +3 more
doaj +1 more source
The Influence of Climate Change on Vector-Borne Diseases in a Wilderness Medicine Context
Wilderness & environmental medicine (Print)The imminent climate crisis has been labeled as the biggest health threat humanity must deal with. Vector-borne disease distribution and transmission as well as the population at risk are influenced to a great degree by environmental and climactic ...
Jonas E. Mertens
semanticscholar +1 more source
Edith Macpherson Park: Testament to a Pioneering Biodynamic Farmer [PDF]
, 2020 A public park is a fitting testament to a pioneer biodynamic and organic farmer. Edith Macpherson Park is a public park, located in Namur Street, Noble Park, a south-east suburb of Melbourne, Victoria, Australia).
Paull, John
core