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Journal of the Neurological Sciences, 2014 To estimate the prevalence of Willis–Ekbom disease (WED) in a racially homogeneous population of adults Amerindians living in rural coastal Ecuador, and to assess the reliability of the International Restless Legs Syndrome Study Group (IRLSSG ...
Pablo Castillo +2 more
exaly +2 more sources
Review of Diagnostic Instruments for the Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED): Critique and Recommendations [PDF]
Journal of Clinical Sleep Medicine, 2014 Richard Allen +2 more
exaly +2 more sources
Review of Quality of Life Instruments for the Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED): Critique and Recommendations [PDF]
Journal of Clinical Sleep Medicine, 2014 Richard Allen +2 more
exaly +2 more sources
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Mood Disorders in Restless Legs Syndrome (Willis-Ekbom Disease)
The Journal of Clinical Psychiatry, 2014Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a sensorimotor disorder that can result in considerable sleep disruption. This narrative review provides an overview of RLS diagnosis and reports epidemiologic evidence for an association between RLS and mood disorders.
Philip M, Becker, Denise, Sharon
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Peripheral hypoxia in restless legs syndrome (Willis-Ekbom disease)
Neurology, 2014A case-control study to measure oxygen and carbon dioxide partial pressures in the legs in order to assess the involvement of peripheral hypoxia or hypercapnia in the pathogenesis of restless legs syndrome (RLS).RLS severity was assessed with a standard questionnaire.
Aaro V, Salminen +2 more
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Dopaminergic Therapy for Restless Legs Syndrome/Willis-Ekbom Disease
Sleep Medicine Clinics, 2015Dopaminergic therapies have been a mainstay of restless legs treatment and are endorsed as first-line therapies by multiple professional societies. This article summarizes the differences and similarities among the dopamine agonists with attention to pharmacology, efficacy, side effects, and dosing.
Rochelle S, Zak, Arthur S, Walters
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Willis-Ekbom disease/restless legs syndrome in patients with opioid withdrawal
Sleep Medicine, 2018Many patients with opioid use disorder report symptoms similar to restless legs syndrome (RLS) during withdrawal. However, whether these symptoms are true RLS, their predictors and effect of treatment with pregabalin are still unknown.A total of 19 consecutive patients with opioid use disorder who were admitted for detoxification were included in this ...
Ravi Gupta, Ramjan Ali, Rajat Ray
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Restless legs syndrome/Willis Ekbom disease: Evaluation and treatment
International Review of Psychiatry, 2014Restless legs syndrome/Willis Ekbom disease (RLS/WED) has been recognized as a significant medical disorder since the 17th century. It was studied mostly in the last 50 years in relation to increasing interest in sleep medicine and health-related quality of life. This led to recognition that the disease is not well characterized as restless feelings in
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An update on restless legs syndrome (Willis-Ekbom disease)
Current Opinion in Neurology, 2014In recent years, there have been a number of advances in the field of restless legs syndrome (RLS) or Willis-Ekbom disease (WED). Here, we review recent studies pertaining to the diagnosis and clinical features, pathogenesis, and treatment of RLS/WED.Recent studies have added a temporal dimension to RLS/WED epidemiology by examining both the incidence ...
Diego, Garcia-Borreguero +1 more
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To what extent and why are COPD and Willis-Ekbom disease associated?
Sleep and Breathing, 2016Willis-Ekbom disease (RLS/WED) is common in chronic obstructive pulmonary disease (COPD). Patients with RLS/WED have poorer quality of sleep and more fatigue and depressive symptoms. The prevalence of RLS/WED in patients with COPD has been reported to vary between 29.1 and 36.8 %.
Tugba, Mandal +5 more
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