Results 71 to 80 of about 1,743 (188)

A Real‐World Study on Unstable Parkinson's Disease: Levodopa Dosage Management and the Role of Nonmotor Symptoms

Movement Disorders Clinical Practice, Volume 12, Issue 12, Page 2143-2153, December 2025.
Abstract Background Parkinson's disease (PD) is a neurodegenerative disorder associated with motor and nonmotor symptoms. Objectives This study assesses levodopa dose management, the therapeutic goals of clinicians, the factors that influence clinicians' choice of therapy, and the role of nonmotor symptoms using real‐world evidence from Germany, Italy,
Fabrizio Stocchi, Jaime Kulisevsky, Wolfgang H. Jost   +2 more
wiley   +1 more source

The impact of rotating work schedules, chronotype, and restless legs syndrome/Willis-Ekbom disease on sleep quality among female hospital nurses and midwives: A cross-sectional survey [PDF]

, 2019
Background: Decreases in subjective sleep quality are prevalent among nurses and midwives engaged in rotating shift work. Objectives: The present study aimed to examine the relationship between differences in work schedules and subjective sleep quality ...
Eto Hiromi, Kato Chiho, Kondo Hideaki, Nagaura Yuki, Uekata Sakura   +4 more
core   +2 more sources

Reply to “Neurophysiological Testing to Diagnose Stiff‐Person Spectrum Disorder”

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 303-304, January 2026.
João Moura, Lorenzo Rocchi, Michael Zandi, Bettina Balint, Kailash P. Bhatia, Anna Latorre   +5 more
wiley   +1 more source

Longitudinal Study of Treatment Variability for Parkinson's Disease across Specialized Centers

Movement Disorders Clinical Practice, Volume 12, Issue 12, Page 2207-2216, December 2025.
Abstract Background Real‐world evidence on treatment practices in Parkinson's disease (PD) has been limited due to the difficulty in collecting comprehensive and generalizable clinical data. Objectives We sought to identify treatment patterns and test how treatment changed in response to (1) falling, (2) worsening disease, and (3) worsening quality of ...
Nabila Dahodwala, Theodore Kapogiannis, Amanda Cruz, James C. Beck, Thomas L. Davis, Hongliang Liu, Sheng Luo, Anna Naito, Marilyn Neault, Miriam R. Rafferty, Adolfo Ramirez‐Zamora, Connie Marras   +11 more
wiley   +1 more source

Animal models of ulcerative colitis and their application in drug research [PDF]

, 2014
The specific pathogenesis underlying inflammatory bowel disease is complex, and it is even more difficult to decipher the pathophysiology to explain for the similarities and differences between two of its major subtypes, Crohn’s disease and ulcerative ...
Low, Daren, Mizoguchi, Emiko, Nguyen, Deanna D   +2 more
core   +1 more source

Characteristics of sleep/wake problems and delivery outcomes among pregnant Japanese women without gestational complications

BMC Pregnancy and Childbirth, 2020
Background Frequently observed sleep/wake problems among pregnant women need comprehensive evaluation. This study was conducted to clarify the sleep/wake problems among pregnant women without gestational complications during the second and third ...
Shiho Umeno, Chiho Kato, Yuki Nagaura, Hideaki Kondo, Hiromi Eto   +4 more
doaj   +1 more source

Dysphagia in Huntington's Disease: An Evaluation of Swallowing Disturbance across the HD‐ISS Staging Spectrum

Movement Disorders Clinical Practice, Volume 12, Issue 12, Page 2296-2303, December 2025.
ABSTRACT Background The onset and pattern of progression of swallowing impairment in HD remain poorly understood. The Swallowing Disturbance Questionnaire (SDQ) has proven useful in assessing dysphagia across various neurological conditions, but its use in HD remains largely unexplored. Objectives To evaluate swallowing difficulties in HD using the SDQ
Japleen Kaur, Krisha Bagga, Paul E. Gilbert, Jody Corey‐Bloom   +3 more
wiley   +1 more source

Restless Legs Syndrome and Parkinson Disease: A Causal Relationship Between the Two Disorders?

Frontiers in Neurology, 2018
Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED) is a common sleep related movement disorder that can be idiopathic or occurs in comorbidity with other medical conditions such as polyneuropathy, iron deficiency anemia, multiple sclerosis ...
Luigi Ferini-Strambi, Luigi Ferini-Strambi, Giulia Carli, Francesca Casoni, Andrea Galbiati, Andrea Galbiati   +5 more
doaj   +1 more source

Compound Heterozygous Structural Variants in Cases with Unsolved PRKN‐Associated Parkinson's Disease

Movement Disorders, Volume 40, Issue 12, Page 2722-2731, December 2025.
Abstract Background Biallelic mutations in the PRKN gene are a common cause of early‐onset Parkinson's disease (EOPD). In addition to single nucleotide variants, structural variants contribute substantially to the mutational profile of PRKN. A significant portion of patients with EOPD remains genetically unsolved.
Agata Fant, Sara Trova, Edoardo Monfrini, Gaia Treves, Francesco Musacchia, Fabio Landuzzi, Paola Mandich, Antonio Amoroso, Remo Sanges, Luca Pandolfini, Francesco Cavallieri, Franco Valzania, Valentina Fioravanti, Giulia Di Rauso, Gloria Brescia, Enza Maria Valente, Valeria Tiranti, Luigi Michele Romito, Chiara Reale, Barbara Garavaglia, Antonio Emanuele Elia, Andrea Cavalli, Alessio Di Fonzo, Manuela Vecchi, Stefano Gustincich   +24 more
wiley   +1 more source

Evaluation of upper endoscopic findings in patients with restless legs syndrome and gastric complaints [PDF]

Arquivos de Neuro-Psiquiatria
Background: The effect of gastrointestinal system disorders on Restless Legs Syndrome/Willis-Ekbom disease (RLS/WED) has been previously demonstrated by using serological tests.
Mustafa ÇAM, Ufuk KUTLUANA
doaj   +2 more sources