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An update on the treatment of Restless Legs Syndrome/Willis-Ekbom Disease: prospects and challenges
Expert Review of Neurotherapeutics, 2018Introduction: Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED) is a sleep disorder characterized by an urge to move the legs, frequently associated or triggered by unpleasant sensations in the lower limbs that affects approximately 2.5% of adults ...
M. Zucconi +4 more
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Restless legs syndrome/Willis Ekbom disease: Evaluation and treatment
International Review of Psychiatry, 2014Restless legs syndrome/Willis Ekbom disease (RLS/WED) has been recognized as a significant medical disorder since the 17th century. It was studied mostly in the last 50 years in relation to increasing interest in sleep medicine and health-related quality of life. This led to recognition that the disease is not well characterized as restless feelings in
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Treatment Options in Intractable Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED)
Current Treatment Options in Neurology, 2016Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED) is a common condition characterized by an irresistible urge to move the legs, concomitant with an unpleasant sensation in the lower limbs, which is typically relieved by movement. Symptoms occur predominantly at rest and prevail in the afternoon or evening.
Rinaldi, Fabrizio +4 more
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Restless legs syndrome/Willis-Ekbom disease in Parkinson’s disease: a cross-sectional analysis
Arquivos de Neuro-PsiquiatriaBackground: Parkinson’s disease (PD) is a neurodegenerative disorder that primarily affects the substantia nigra pars compacta and basal ganglia, leading to the characteristic motor symptoms of the disease: bradykinesia, resting tremor, and muscle ...
Agatha Lopes Azedo +9 more
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Restless Legs Syndrome (Willis–Ekbom Disease) in the Older Person
Aging Health, 2012Restless legs syndrome (RLS) is a common condition characterized by uncomfortable sensations deep in the legs, developing at rest, that compel the person to move. Symptoms are worst at night and sleep disturbance is common. RLS occurs in 7–11% of the population in western countries, and is increasingly common in older people. Primary RLS is familial in
Helen O‘Brien, Shaun T O‘Keeffe
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Misdiagnosing restless legs syndrome/Willis-Ekbom disease despite the IRLSSG criteria
Sleep Medicine, 2020Karla Carlos +2 more
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History of Restless Legs Syndrome, Recently Named Willis–Ekbom Disease
2015After being recognized as a syndrome, Willis–Ekbom disease (WED) had been essentially ignored for three centuries until the excellent work of Ekbom in the mid-twentieth-century, carefully describing his case series. Shortly thereafter, attention to disorders disturbing sleep increased with advent of the discipline of sleep medicine.
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