Results 61 to 70 of about 2,742 (232)

Levodopa‐Carbidopa Intestinal Gel Improves Dyskinesia in Parkinson's Disease: Post Hoc Analysis from the COSMOS Study

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 1, Page 98-107, January 2026.
Abstract Background Dyskinesia is a debilitating complication of dopaminergic therapy in advanced Parkinson's disease. Objectives To evaluate the effect of levodopa‐carbidopa intestinal gel (LCIG) on dyskinesia burden. Methods This is a post hoc analysis of the retrospective, observational COmedication Study assessing Mono‐ and cOmbination therapy with
Alfonso Fasano   +11 more
wiley   +1 more source

Functional connectivity and topology in patients with restless legs syndrome: a case–control resting-state functional magnetic resonance imaging study [PDF]

open access: yes, 2021
Background and purpose: Functional connectivity studies revealed alterations within thalamic, salience, and default mode networks in restless legs syndrome patients.
Frauscher B.   +8 more
core   +1 more source

Subcutaneous Apomorphine Infusion Initiation Is Associated with Impulse Control Disorder Attenuation in Advanced Parkinson's Disease Patients: Insights from the French NS‐Park Cohort

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 1, Page 142-153, January 2026.
Abstract Background Impulse control disorders (ICD) are common non‐motor complications in Parkinson's disease (PD), particularly in patients receiving oral dopamine agonists (DA). Continuous subcutaneous apomorphine infusion (CSAI) is a device‐aided therapy for advanced PD, but its effects on ICD remain underexplored in real‐world settings.
Clément Desjardins   +249 more
wiley   +1 more source

Cognitive Resilience in Willis Ekbom Disease: Enhancing Functionality through Neurophysiotherapy Interventions

open access: yesJournal of Clinical and Diagnostic Research
Introduction: The neurological condition known as Restless Legs Syndrome (RLS), or Willis-Ekbom disease, is epitomised by unintentional movement of the legs that predominantly unfold during sleep. RLS is accompanied by leg discomfort.
Muskan, Shweta Sharma
semanticscholar   +1 more source

The Parkinson's disease and restless legs syndrome/Willis-Ekbom disorder link: evidences, biases and clinical relevance

open access: yesArquivos de Neuro-Psiquiatria
Parkinson's disease (PD) and restless legs syndrome/Willis-Ekbom disorder (RLS/WED) are relatively common diseases in the realm of movement disorders.
Renato Puppi Munhoz   +2 more
doaj   +1 more source

Efficacy and Safety of Foslevodopa/Foscarbidopa Monotherapy in Patients with Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 1, Page 181-190, January 2026.
Abstract Background As Parkinson's disease (PD) progresses, managing symptoms becomes increasingly difficult. Foslevodopa/foscarbidopa (LDp/CDp), a 24‐hour/day continuous subcutaneous infusion of levodopa/carbidopa (LD/CD) prodrugs, improves motor complications.
Jason Aldred   +11 more
wiley   +1 more source

Orthostatic Tremor Is Evoked by Muscle Load Without the Need for Orthostatic Position

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 1, Page 208-215, January 2026.
Abstract Background Primary orthostatic tremor (POT) is a rare movement disorder characterized by a high‐frequency tremor and a considerable feeling of unsteadiness. People with POT are significantly affected in their daily activities and have reduced quality of life.
Karolina af Edholm   +4 more
wiley   +1 more source

Evaluation of Restless Leg Syndrome in Patients with Non-Dialysis Dependent Chronic Kidney Disease at Fatima Memorial Hospital Lahore: A Cross-sectional Study

open access: yesLife and Science
Objective: To determine the occurrence of restless leg syndrome in individuals with non-dialysis-dependent chronic kidney disease. Study Design: A descriptive cross-sectional study.
Bilal Basit   +5 more
doaj   +1 more source

Evaluation of Sleep Quality in Pregnancy According to Trimesters and Investigation of Related Factors

open access: yesTürk Uyku Tıbbı Dergisi, 2023
Objective:Pregnancy causes changes in the duration and quality of sleep. Insomnia, insufficient sleep time, and symptoms associated with restless legs syndrome/Willis-Ekbom disease (RLS/WED) are frequently described during pregnancy. We aimed to evaluate
Mustafa Karadeniz   +2 more
doaj   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 1, Page 44-59, January 2026.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn   +18 more
wiley   +1 more source

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