Results 1 to 10 of about 47,034 (186)
Distinct pathways for genetic and epigenetic predisposition in familial and bilateral Wilms tumor [PDF]
Background Genetic predisposition is particularly common in children with the kidney cancer, Wilms tumor. In 10% of these children, this manifests as a family history of Wilms tumor or bilateral disease.
Jenny Wegert +31 more
doaj +2 more sources
Significant improvement has been made in the treatment of children with Wilms tumor. New protocols are in place designed to maintain a high rate of cure for these patients while minimizing toxicity, based on refinement of the risk-stratification system.
F, Seseke, P, Gutjahr, B, Kremens
openaire +6 more sources
Morphoproteomic profiling of the mammalian target of rapamycin (mTOR) signaling pathway in desmoplastic small round cell tumor (EWS/WT1), Ewing's sarcoma (EWS/FLI1) and Wilms' tumor(WT1). [PDF]
BackgroundDesmoplastic small round cell tumor (DSRCT) is a rare sarcoma in adolescents and young adults. The hallmark of this disease is a EWS-WT1 translocation resulting from apposition of the Ewing's sarcoma (EWS) gene with the Wilms' tumor (WT1) gene.
Anderson, Pete M +6 more
core +14 more sources
Knockdown of SENP1 inhibits HIF-1α SUMOylation and suppresses oncogenic CCNE1 in Wilms tumor
Based on our initial bioinformatics finding of the upregulated expression of sentrin-specific protease 1 (SENP1) and cyclin E1 (CCNE1) in Wilms tumor, this study aimed to illustrate the molecular mechanism of SENP1 in Wilms tumor, which involved the ...
Shibo Zhu +6 more
doaj +1 more source
Wilms' tumor also called as nephroblastoma is commonly seen extracranial solid tumor involving kidneys in children. Rarely, Wilms' tumor can arise from ectopic nephrogenic remnants located outside the kidneys.
Vankadari Kousik +3 more
doaj +1 more source
CLINICAL EXPERIENCE IN THE MANAGEMENT OF PEDIATRIC WILMS TUMOR [PDF]
Wilms tumor is the commonest renal tumor in children. This study aimed to evaluate the characteristics, diagnosis, treatment, and outcome of Wilms tumor in pediatric age group and to analyze factors affecting the outcome.
Haithem Almoamin +3 more
doaj +1 more source
Recent Improvements in Adult Wilms Tumor Diagnosis and Management: Review of Literature
Wilms tumor, also denoted as nephroblastoma, an embryonal type of renal cancer, is the most common cancer that affects children in the first 5 years of life. Wilms tumor is very rarely seen in adults.
Vishnupriya Sakthivel +2 more
doaj +1 more source
Congestive heart failure and hypertension associated with Wilms tumor
Wilms tumor is the most common primary renal tumor in children. Wilms tumor has infrequently been reported to present associated with dilated cardiomyopathy and congestive heart failure.
Sarah C. Stokes +3 more
doaj +1 more source
AbstractThe objectives for the treatment of Wilms tumor in both the Children's Oncology Group (COG) and the International Society of Paediatric Oncology (SIOP) have focused on improving cure rates and minimizing toxicity by limiting the use of radiation and doxorubicin.
Luke Pater +6 more
openaire +2 more sources
Wilms or non-Wilms tumors? Imaging features of renal tumors in pediatrics
Introduction: Identifying the imaging features of renal tumors in pediatric population allows reaching more accurate diagnoses and implementing more appropriate treatments.
Mónica Rocío Royero-Arias +2 more
doaj +1 more source

