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Artificial intelligence can help individualize wilms tumor treatment by predicting tumor response to preoperative chemotherapy

open access: diamond
Ahmed Nashat   +12 more
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Characterization and comparative profiling of piRNAs in serum biopsies of pediatric Wilms tumor patients. [PDF]

open access: yesCancer Cell Int
Mohamed FS   +6 more
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Wilms Tumor

Urologic Clinics of North America, 2023
Wilms tumor (WT), or nephroblastoma, is the most common primary malignant renal tumor of childhood. It is an embryonal tumor that develops from remnants of immature kidney. There are approximately 500 new WT cases diagnosed in the United States every year.
Amanda F, Saltzman   +2 more
openaire   +2 more sources

MicroRNA-483-3p Promotes Proliferation, Migration, and Invasion and Induces Chemoresistance of Wilms’ Tumor Cells

Pediatric and Developmental Pathology, 2020
Wilms’ tumor is the most common pediatric renal malignancy. MiRNAs are important regulators in multiple cancers including Wilms’ tumor. In this study, we examined the role of miR-483-3p on proliferation, chemosensitivity, migration, and invasion of Wilms’
Guanghua Che   +5 more
semanticscholar   +1 more source

WILMS' TUMOR

Pediatric Clinics of North America, 1997
Wilms' tumor is the most common renal malignancy of childhood. Survival rates for favorable histology of Wilms' tumor currently approach 90%. Recent advances in the molecular genetics of Wilms' tumor have led to insights into the genetic factors involved in the development of Wilms' tumor, normal renal development, and the mechanisms of tumorigenesis.
M J, Petruzzi, D M, Green
openaire   +2 more sources

METTL3 polymorphisms and Wilms tumor susceptibility in Chinese children: A five‐center case–control study

Journal of Gene Medicine, 2020
Wilms tumor is a common pediatric tumor worldwide. Methyltransferase like 3 (METTL3) is a core gene of the N6‐methyladenosine (m6A) modification that widely affects the transcription of tumor‐related genes in eukaryotes.
A. Lin   +9 more
semanticscholar   +1 more source

Wilms' tumor

Pediatric Nephrology, 1992
In the last 2 decades, important advances in the treatment of Wilms' tumor have been made. The remarkable improvement in survival in these patients has been the product of new surgical techniques, classification of the tumors into prognostic stages upon initial presentation and the tailoring of chemotherapy and radiation therapy thus permitted. A brief
R P, Warrier, O, Regueira
openaire   +2 more sources

Physiological functions of Wilms’ tumor 1‐associating protein and its role in tumourigenesis

Journal of Cellular Biochemistry, 2019
The Wilms’ tumor‐associated gene WT1 encodes a tumor suppressor gene, which is implicated in renal differentiation and development of adult urogenital system.
Wenli Xie   +5 more
semanticscholar   +1 more source

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