Results 21 to 30 of about 3,009,060 (331)
Recent advances in Wilms tumor predisposition.
Human Molecular Genetics, 2020 Wilms tumor (WT), the most common childhood kidney cancer, develops in association with an underlying germline predisposition in up to 15% of cases. Germline alterations affecting the WT1 gene and epigenetic alterations affecting the 11p15 locus are ...
J. Maciaszek, Ninad Oak, K. Nichols
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Clinical Pediatric Hematology-Oncology, 2023 Nephroblastomatosis (NBM) is a precursor of Wilms tumor. We herein report a case in which Wilms tumor was initially suspected and the affected kidney was removed. The tumor was subsequently diagnosed as intralobar NBM and a favorable outcome was achieved
Hirozumi Sano +8 more
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Cancer, 2020 WAGR syndrome (Wilms tumor, aniridia, genitourinary anomalies, and range of developmental delays) is a rare contiguous gene deletion syndrome with a 45% to 60% risk of developing Wilms tumor (WT). Currently, surveillance and treatment recommendations are
Janna A. Hol +20 more
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Handbook of Pediatric Hematology and Oncology, 2019 Wilms tumor is often first noticed because of abdominal swelling or a mass in the kidney that can be felt upon physical examination. Some affected children have abdominal pain, fever, a low number of red blood cells (anemia), blood in the urine ...
Naim K
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Journal of Family Medicine and Primary Care, 2019 Wilms' tumor is most common pediatric renal tumor. Teratoid Wilms' tumor is a variant of Wilms' tumor, in which heterologous tissue predominates. Most commonly, epithelial and mesenchymal tissue present as heterologous component.
Santosh G Rathod +3 more
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Sphingosine 1-phosphate in renal diseases [PDF]
, 2013 Because of its highly bioactive properties sphingosine 1-phosphate (S1P) is an attractive target for the treatment of several diseases. Since the expression of sphingosine kinases as well as S1P receptors was demonstrated in the kidney, questions about ...
Huwiler, Andrea +2 more
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Embryonal precursors of Wilms tumor
Science, 2019 A childhood tumor—from the beginning Many adult cancers arise from clonal expansions of mutant cells in normal tissue. These premalignant expansions are defined by somatic mutations shared by the cancers.
Tim H. H. Coorens +40 more
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ALKBH5 gene polymorphisms and Wilms tumor risk in Chinese children: A five‐center case‐control study
Journal of clinical laboratory analysis (Print), 2020 Wilms tumor is a frequently diagnosed renal cancer among children with unclear genetic causes. N6‐methyladenosine (m6A) modification genes play critical roles in tumorigenesis.
Rui-Xi Hua +10 more
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Asymptomatic adult Wilms' tumor: A case report
Radiology Case Reports, 2022 Background: Wilms' tumor, also called nephroblastoma, is an extremely uncommon kidney tumor of adulthood. We reported a adult man with a left kidney mass diagnosed as Wilms' tumor.Case presentation: A 25-year-old man was hospitalized due to injury of the
Yu-Feng Bai, BSc +8 more
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Changes in renal WT-1 expression preceding hypertension development [PDF]
, 2016 Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica +8 more
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