Results 91 to 100 of about 1,752,983 (309)

Low-level jets in the North and Baltic seas: mesoscale model sensitivity and climatology using WRF V4.2.1 [PDF]

Geoscientific Model Development
Low-level jets (LLJs), characterized by wind speed maxima in the lower part of the atmospheric boundary layer, play a crucial role in shaping wind resource availability, particularly as modern wind turbines reach heights exceeding 200 m.
B. T. E. Olsen, A. N. Hahmann, N. G. Alonso-de-Linaje, M. Žagar, M. Dörenkämper   +4 more
doaj   +1 more source

Using bias-corrected reanalysis to simulate current and future wind power output

, 2016
Reanalysis models are rapidly gaining popularity for simulating wind power output due to their convenience and global coverage. However, they should only be relied upon once thoroughly proven.
I. Staffell, S. Pfenninger
semanticscholar   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Optimal Management of a Wind/CAES Power Plant by means of Neural Network Wind Speed Forecast

, 2007
Some of the major limitations of renewable energy sources are represented by their low power density and intermittent nature, largely depending upon local site and unpredictable weather conditions. These problems concur to increase the unit costs of wind
Vincenzo Marano, Gianfranco Rizzo, MARANO, VINCENZO, Ivan Arsie, ARSIE, Ivan, Michael Moran, RIZZO, Gianfranco, Giuseppe Savino   +7 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Pedestrian level wind environment around isolated buildings resulted from twisted wind profiles

, 2015
The pedestrian-level wind environment influenced by twisted wind profiles were evaluated through a series of wind tunnel tests. In the tests, more than 200 Irwin sensors were installed to measure the wind speeds at pedestrian level around five isolated ...
Tse, Kam-Tim, Kwok, Kenny C. S. (R14040), Zhang, Xuelin, Weerasuriya, Asiri U.   +3 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source