Results 201 to 210 of about 3,702,210 (399)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Measurement uncertainty of IR thermographic flow visualization measurements for transition detection on wind turbines in operation

, 2018
Christoph Dollinger, Michael Sorg, Nicholas Balaresque, Andreas Fischer   +3 more
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Towards high resolution, validated and open global wind power assessments. [PDF]

Nat Commun
Peña-Sánchez EU, Dunkel P, Winkler C, Heinrichs H, Prinz F, Weinand JM, Maier R, Dickler S, Chen S, Gruber K, Klütz T, Linßen J, Stolten D.   +12 more
europepmc   +1 more source

Relationship between wind speed and gas exchange over the ocean revisited

, 2014
R. Wanninkhof
semanticscholar   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

'Chinook Winds' [PDF]

Science, 1886
  +7 more sources

Effects of ambient wind on droplet deposition uniformity in orchard air-assisted sprayers. [PDF]

Sci Rep
Xu T, Li X, Ding L, Qi Y, Lu H, Xiao W, Lv X, Li J.   +7 more
europepmc   +1 more source

Wind accretion: Theory and observations [PDF]

, 2015
N. I. Shakura, K. A. Postnov, A. Yu. Kochetkova, L. Hjalmarsdotter, L. Sidoli, A. Paizis   +5 more
openalex   +1 more source